Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 4/20 | 0.33 |
| ▸ | RAB9A | P51151 | 4/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | TAS2R8 | Q9NYW2 | 1/20 | 0.31 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.31 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.31 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17416594 | 0.94 | PLK1 (0.36) | PLK1NPC1RAB9ASMN1; SMN2GAA | |
| SCHEMBL17416643 | 0.93 | PLK1 (0.36) | PLK1NPC1RAB9ASMN1; SMN2GAA | |
| SCHEMBL17416648 | 0.91 | ABCB1 (0.34) | NPC1RAB9AGAAMAPTTP53 | |
| SCHEMBL29684619 | 0.88 | PLK1 (0.35) | PLK1NPC1RAB9ASMN1; SMN2GAA | |
| SCHEMBL667491 | 0.88 | PLK1 (0.35) | PLK1NPC1RAB9ASMN1; SMN2GAA | |
| SCHEMBL17416615 | 0.85 | ABCB1 (0.36) | NPC1RAB9ASMN1; SMN2GAAMAPT | |
| SCHEMBL17416646 | 0.84 | ABCB1 (0.32) | NPC1RAB9AGAAMAPTTP53 | |
| SCHEMBL667440 | 0.84 | PLK1 (0.37) | PLK1NPC1RAB9ASMN1; SMN2GAA | |
| SCHEMBL29684483 | 0.84 | PLK1 (0.37) | PLK1NPC1RAB9ASMN1; SMN2GAA | |
| SCHEMBL667482 | 0.82 | PLK1 (0.37) | PLK1NPC1RAB9ASMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2460786-B1 | Bioavailable diacylhydrazine ligands for modulating the expression of exogenous genes via an ecdysone receptor complex | INTREXON CORP (US) | 2016-01-13 | — | — | EP | claimed |