Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17416648 | 0.94 | ABCB1 (0.34) | ABCB1CYP3A4MAPTTP53HSD17B10 | |
| SCHEMBL17416589 | 0.91 | MAPT (0.35) | ABCB1CYP3A4MAPTTP53RXFP1 | |
| SCHEMBL17416594 | 0.91 | PLK1 (0.36) | MAPTTP53MAPK1HSD17B10NPC1 | |
| SCHEMBL17416646 | 0.85 | ABCB1 (0.32) | ABCB1CYP3A4MAPTTP53HSD17B10 | |
| SCHEMBL17416622 | 0.85 | PLK1 (0.35) | MAPTTP53MAPK1NPC1RAB9A | |
| SCHEMBL29684694 | 0.85 | ABCB1 (0.39) | ABCB1CYP3A4MAPTUSP2ALOX15 | |
| SCHEMBL667409 | 0.85 | ABCB1 (0.39) | ABCB1CYP3A4MAPTUSP2ALOX15 | |
| SCHEMBL12841128 | 0.83 | ABCB1 (0.36) | ABCB1CYP3A4MAPTUSP2ALOX15 | |
| SCHEMBL29685124 | 0.79 | ABCB1 (0.38) | ABCB1CYP3A4MAPTNPC1RAB9A | |
| SCHEMBL668095 | 0.79 | ABCB1 (0.38) | ABCB1CYP3A4MAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2460786-B1 | Bioavailable diacylhydrazine ligands for modulating the expression of exogenous genes via an ecdysone receptor complex | INTREXON CORP (US) | 2016-01-13 | — | — | EP | claimed |