SCHEMBL1741683

SCHEMBL1741683

c1ccc2c(NC3=NCCN3)cccc2c1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADRA2A P08913 9/20 0.62
ADRA2B P18089 6/20 0.62
ADRA2C P18825 6/20 0.62
ADRA1A P35348 4/20 0.62
ADRA1D P25100 3/20 0.62
ADRA1B P35368 3/20 0.62
HTR7 P34969 2/20 0.56
NISCH Q9Y2I1 2/20 0.51
LMNA P02545 2/20 0.51
MEN1 O00255 1/20 0.51
SLC22A1 O15245 1/20 0.51
SLC22A3 O75751 1/20 0.51
HTR1A P08908 1/20 0.51
CYP2D6 P10635 1/20 0.51
CYP2C9 P11712 1/20 0.51
HRH2 P25021 1/20 0.51
CYP2C19 P33261 1/20 0.51
OPRK1 P41145 1/20 0.51
KMT2A Q03164 1/20 0.51
HIF1A Q16665 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30357746 1.00 ADRA2A (0.62) ADRA2AADRA2BADRA2CADRA1AADRA1D
SCHEMBL11199497 0.86 NISCH (0.50) ADRA2AADRA2BADRA2CADRA1AADRA1D
SCHEMBL11153704 0.84 ADRA2A (0.52) ADRA2AADRA2BADRA2CADRA1AADRA1D
SCHEMBL10800017 0.83 ADRA2A (0.55) ADRA2AADRA2BADRA2CADRA1AADRA1D
SCHEMBL11190493 0.77 ADRA2A (0.54) ADRA2AADRA2BADRA2CADRA1AADRA1D
SCHEMBL6581888 0.77 ADRA2A (0.54) ADRA2AADRA2BADRA2CADRA1AADRA1D
SCHEMBL17887760 0.77 ADRA2A (0.66) ADRA2AADRA2BADRA2CADRA1AADRA1D
SCHEMBL27273591 0.77 ADRA2A (0.66) ADRA2AADRA2BADRA2CADRA1AADRA1D
SCHEMBL8020019 0.77 ADRA2A (1.00) ADRA2AADRA2BADRA2CADRA1AADRA1D
SCHEMBL11859273 0.77 ADRA2A (0.68) ADRA2AADRA2BADRA2CADRA1AADRA1D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115516041-B Curing catalyst for curing polymer, method for producing same, moisture-curable composition, and method for producing cured product 日东化成株式会社 2024-06-28 CN disclosed
WO-2024033348-A1 COMBINATION OF CATALYTIC COMPONENTS POLYU GMBH (DE) 2024-02-15 WO disclosed
EP-4321573-A1 COMBINATION OF CATALYTIC COMPONENTS PolyU GmbH (DE) 2024-02-14 EP disclosed
EP-2837660-B1 CURABLE COMPOSITION, AND CURED SYNTHETIC RESIN USING SAME UNIV MIE (JP) 2021-07-14 EP disclosed
EP-2388297-B1 CURABLE COMPOSITION AND CURED OBJECT FORMED THEREFROM KANEKA CORP (JP) 2020-08-19 EP disclosed
US-10301433-B2 Curable organopolysiloxane compositions WACKER CHEMIE AG (DE) 2019-05-28 US disclosed
EP-3172178-B1 CURABLE ORGANOPOLYSILOXANE COMPOSITIONS WACKER CHEMIE AG (DE) 2018-09-12 EP disclosed
US-20170210856-A1 CURABLE ORGANOPOLYSILOXANE COMPOSITIONS WACKER CHEMIE AG (DE) 2017-07-27 US disclosed
EP-2267083-B1 CURABLE COMPOSITION AND CURED MATERIAL KANEKA CORP (JP) 2017-06-21 EP disclosed
EP-3172178-A1 CURABLE ORGANOPOLYSILOXANE COMPOSITIONS Wacker Chemie AG (DE) 2017-05-31 EP disclosed
EP-2267083-A1 CURABLE COMPOSITION AND CURED MATERIAL Kaneka Corporation (JP) 2010-12-29 EP disclosed
EP-1985666-B1 CURABLE COMPOSITION KANEKA CORP (JP) 2010-12-15 EP disclosed
EP-1988127-B1 CURABLE COMPOSITION KANEKA CORP (JP) 2010-12-15 EP disclosed
EP-1990371-B1 CURABLE COMPOSITION KANEKA CORP (JP) 2010-05-05 EP disclosed
US-20090186993-A1 CURABLE COMPOSITION KANEKA CORPORATION (JP) 2009-07-23 US disclosed
US-20090182091-A1 CURABLE COMPOSITION KANEKA CORPORATION (JP) 2009-07-16 US disclosed
US-20090182099-A1 CURABLE COMPOSITION KANEKA CORPORATION (JP) 2009-07-16 US disclosed
EP-1990371-A1 CURABLE COMPOSITION Kaneka Corporation (JP) 2008-11-12 EP disclosed
EP-1988127-A1 CURABLE COMPOSITION Kaneka Corporation (JP) 2008-11-05 EP disclosed
EP-1985666-A1 CURABLE COMPOSITION Kaneka Corporation (JP) 2008-10-29 EP disclosed