⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2535847 | 0.92 | — | — | |
| SCHEMBL2533087 | 0.90 | — | — | |
| SCHEMBL1722024 | 0.82 | — | — | |
| SCHEMBL3793985 | 0.82 | ALDH1A1 (0.36) | — | |
| SCHEMBL22071625 | 0.79 | ALDH1A1 (0.35) | — | |
| SCHEMBL4247604 | 0.77 | — | — | |
| SCHEMBL687389 | 0.77 | — | — | |
| SCHEMBL6225492 | 0.75 | ALDH1A1 (0.39) | — | |
| Ammonia Solution, Strong SCHEMBL9170626 | 0.74 | — | — | |
| SCHEMBL6262427 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2387565-B1 | 2,4-PYRIMIDINEDIAMINE COMPOUNDS FOR TREATMENT OF INFLAMMATORY DISORDERS | RIGEL PHARMACEUTICALS INC (US) | 2016-12-14 | — | — | EP | disclosed |
| CN-102317265-B | 2,4-PYRIMIDINEDIAMINE COMPOUNDS FOR TREATMENT OF INFLAMMATORY DISORDERS | RIGEL PHARMACEUTICALS INC | 2015-03-25 | — | — | CN | disclosed |
| US-8575165-B2 | Methods for treating inflammatory disorders using 2,4-pyrimidinediamine compounds | RIGEL PHARMACEUTICALS, INC. (US) | 2013-11-05 | — | — | US | disclosed |
| US-8334297-B2 | 2,4-pyrimidinediamine compounds for treatment of inflammatory disorders | RIGEL PHARMACEUTICALS INC. (US) | 2012-12-18 | — | — | US | disclosed |
| CN-102317265-A | 2,4-PYRIMIDINEDIAMINE COMPOUNDS FOR TREATMENT OF INFLAMMATORY DISORDERS | RIGEL PHARMACEUTICALS INC | 2012-01-11 | — | — | CN | disclosed |
| EP-2387402-A2 | METHODS FOR TREATING INFLAMMATORY DISORDERS USING 2,4-PYRIMIDINEDIAMINE COMPOUNDS | Rigel Pharmaceuticals, Inc. (US) | 2011-11-23 | — | — | EP | disclosed |
| EP-2387565-A2 | 2,4-PYRIMIDINEDIAMINE COMPOUNDS FOR TREATMENT OF INFLAMMATORY DISORDERS | Rigel Pharmaceuticals, Inc. (US) | 2011-11-23 | — | — | EP | disclosed |
| US-8044070-B2 | Heteroaryloxy nitrogenous saturated heterocyclic derivative | MSD K.K. (JP) | 2011-10-25 | — | — | US | disclosed |
| US-8038799-B2 | Substrate processing apparatus and substrate processing method | KURITA WATER INDUSTRIES LTD. (JP) | 2011-10-18 | — | — | US | disclosed |
| US-8038847-B2 | Structured forming fabric, papermaking machine and method | VOITH PATENT GMBH (DE) | 2011-10-18 | — | — | US | disclosed |
| US-20060178375-A1 | Heteroaryloxy nitrogenous saturated heterocyclic derivative | MSD K.K. (JP) | 2006-08-10 | — | — | US | disclosed |
| CN-1812981-A | Heteroaryloxy nitrogenous saturated heterocyclic derivative | BANYU PHARMA CO LTD (JP) | 2006-08-02 | — | — | CN | disclosed |
| EP-1642898-A1 | HETEROARYLOXY NITROGENOUS SATURATED HETEROCYCLIC DERIVATIVE | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2006-04-05 | — | — | EP | disclosed |
| EP-0619345-B1 | Phthalocyanine compound and optical recording medium containing it | MITSUI CHEMICALS INC (JP) | 1999-08-25 | — | — | EP | disclosed |
| US-5750229-A | Phthalocyanine compound and optical recording medium containing it | MITSUI TOATSU CHEMICALS, INC. (JP) | 1998-05-12 | — | — | US | disclosed |
| US-5646273-A | FOR USE IN OPTICAL DISKS | MITSUI TOATSU CHEMICALS, INC. (JP) | 1997-07-08 | — | — | US | disclosed |
| EP-0619345-A1 | Phthalocyanine compound and optical recording medium containing it | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1994-10-12 | — | — | EP | disclosed |
| US-4552886-A | Fungicidal pyridylmethyl-amines | ELI LILLY AND COMPANY (US) | 1985-11-12 | — | — | US | disclosed |
| US-4501746-A | HERBICIDES; PLANT GROWTH REGULATORS | ELI LILLY AND COMPANY (US) | 1985-02-26 | — | — | US | disclosed |
| EP-0097013-A2 | Fungicidal heterocyclic amines | ELI LILLY AND COMPANY (US) | 1983-12-28 | — | — | EP | disclosed |