⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13402590 | 0.74 | — | — | |
| SCHEMBL11202591 | 0.74 | — | — | |
| SCHEMBL7002117 | 0.71 | — | — | |
| SCHEMBL9745900 | 0.69 | — | — | |
| SCHEMBL9743296 | 0.69 | — | — | |
| SCHEMBL17854047 | 0.65 | MAPT (0.41) | — | |
| SCHEMBL17232333 | 0.65 | — | — | |
| SCHEMBL10784603 | 0.64 | DAO (0.31) | — | |
| SCHEMBL8292939 | 0.64 | MAOA (0.55) | — | |
| SCHEMBL14395012 | 0.64 | MAOA (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111220741-B | Method for separating and screening sweet components of scorched sweet flavor in Sanming Yuxi tobacco leaves | 福建中烟工业有限责任公司 | 2022-09-30 | — | — | CN | claimed |
| CN-111220741-A | Method for separating and screening sweet components of scorched sweet flavor in Sanming Yuxi tobacco leaves | 福建中烟工业有限责任公司 | 2020-06-02 | — | — | CN | claimed |
| CN-111220741-B | Method for separating and screening sweet components of scorched sweet flavor in Sanming Yuxi tobacco leaves | 福建中烟工业有限责任公司 | 2022-09-30 | — | — | CN | disclosed |
| EP-3400250-B1 | PROCESS FOR PREPARING GRAFT COPOLYMER COMPRISING POLYETHYLENE | SABIC GLOBAL TECHNOLOGIES BV (NL) | 2022-04-20 | — | — | EP | disclosed |
| CN-107522605-B | Sesquiterpene methyl cyclopentene dione, its preparation method and application | 中国科学院南海海洋研究所 | 2021-01-29 | — | — | CN | disclosed |
| CN-111220741-A | Method for separating and screening sweet components of scorched sweet flavor in Sanming Yuxi tobacco leaves | 福建中烟工业有限责任公司 | 2020-06-02 | — | — | CN | disclosed |
| US-9278909-B2 | Amide-extended crosslinking compounds and methods for use thereof | DESIGNER MOLECULES, INC. (US) | 2016-03-08 | — | — | US | disclosed |
| US-9051354-B2 | Protein charge regulator and protein-encapsulating polymer micelle complex | THE UNIVERSITY OF TOKYO (JP) | 2015-06-09 | — | — | US | disclosed |
| US-20140243333-A1 | SYNTHESIS OF FUNCTIONALIZED OCTAHYDRO-ISOQUINOLIN-1-ONE-8-CARBOXYLIC ESTERS AND ANALOGS, AND THERAPEUTIC METHODS | UNIVERSITY OF KANSAS (US) | 2014-08-28 | — | — | US | disclosed |
| US-20140243333-A1 | SYNTHESIS OF FUNCTIONALIZED OCTAHYDRO-ISOQUINOLIN-1-ONE-8-CARBOXYLIC ESTERS AND ANALOGS, AND THERAPEUTIC METHODS | UNIVERSITY OF KANSAS (US) | 2014-08-28 | — | — | US | disclosed |
| US-8735391-B2 | Synthesis of functionalized octahydro-isoquinolin-1-one-8-carboxamides, octahydro-isoquinolin-1-one-8-carboxylic esters and analogs, and therapeutic methods | UNIVERSITY OF KANSAS (US) | 2014-05-27 | — | — | US | disclosed |
| EP-2388297-A1 | CURABLE COMPOSITION AND CURED OBJECT FORMED THEREFROM | Kaneka Corporation (JP) | 2011-11-23 | — | — | EP | disclosed |
| US-20110130485-A1 | IMIDE-LINKED MALEIMIDE AND POLYMALEIMIDE COMPOUNDS | DESIGNER MOLECULES, INC. (US) | 2011-06-02 | — | — | US | disclosed |
| US-20110092547-A1 | CHEMICAL COMPOUNDS 979 | ASTRAZENECA AB (SE) | 2011-04-21 | — | — | US | disclosed |
| US-7884174-B2 | condensation of appropriate anhydrides with appropriate diamines to give amine terminated compounds, then condensed with excess maleic anhydride to yield imide-extended maleimide compounds | DESIGNER MOLECULES, INC. (US) | 2011-02-08 | — | — | US | disclosed |
| US-20100256142-A1 | SYNTHESIS OF FUNCTIONALIZED OCTAHYDRO-ISOQUINOLIN-1-ONE-8- CARBOXAMIDES, OCTAHYDRO-ISOQUINOLIN-1-ONE-8-CARBOXYLIC ESTERS AND ANALOGS, AND THERAPEUTIC METHODS | UNIVERSITY OF NORTH CAROLINA | 2010-10-07 | — | — | US | disclosed |
| US-20100256142-A1 | SYNTHESIS OF FUNCTIONALIZED OCTAHYDRO-ISOQUINOLIN-1-ONE-8- CARBOXAMIDES, OCTAHYDRO-ISOQUINOLIN-1-ONE-8-CARBOXYLIC ESTERS AND ANALOGS, AND THERAPEUTIC METHODS | UNIVERSITY OF NORTH CAROLINA | 2010-10-07 | — | — | US | disclosed |
| WO-2010037050-A2 | SYNTHESIS OF FUNCTIONALIZED OCTAHYDRO-ISOQUINOLIN-1-ONE-8-CARBOXAMIDES, OCTAHYDRO-ISOQUINOLIN-1-ONE-8-CARBOXYLIC ESTERS AND ANALOGS, AND THERAPEUTIC METHODS | UNIVERSITY OF KANSAS (US) | 2010-04-01 | — | — | WO | disclosed |
| US-20080075961-A1 | Imide-linked maleimide and polymaleimide compounds | DESIGNER MOLECULES, INC. | 2008-03-27 | — | — | US | disclosed |
| US-20070141021-A1 | Methylmaleimidyl polymer derivatives | SUN BIO, INC. | 2007-06-21 | — | — | US | disclosed |