SCHEMBL174227

SCHEMBL174227

CCc1cc(N)n[nH]1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrazine SCHEMBL6633032 0.96 HCAR2 (0.46)
SCHEMBL1706467 0.82
Hydrochloric Acid SCHEMBL1707357 0.80 NPC1 (0.54)
SCHEMBL9140451 0.79 HCAR2 (0.54)
SCHEMBL23500955 0.78
SCHEMBL2173940 0.78
SCHEMBL19732648 0.77
SCHEMBL2865249 0.77 HCAR2 (0.56)
SCHEMBL21737077 0.76
SCHEMBL29428236 0.76 DYRK1A (0.41)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 249 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4695238-A1 CDK2 INHIBITORS Blueprint Medicines Corporation (US) 2026-02-18 EP disclosed
US-20250333414-A1 HETARYL SUBSTITUTED INDAZOLES AND BENZIMIDAZOLES AS STING ANTAGONISTS AND THE USE THEREOF AS MEDICAMENT BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) 2025-10-30 US disclosed
US-20250276966-A1 Nitrogen-Linked Benzisoxazole Sulfonamide Derivatives PFIZER (US) 2025-09-04 US disclosed
CN-116003441-B Heteroaromatic derivative regulator, preparation method and application thereof 江苏豪森药业集团有限公司 2025-06-10 CN disclosed
US-20250122183-A1 Nitrogen-Linked Benzisoxazole Sulfonamide Derivatives PFIZER (US) 2025-04-17 US disclosed
WO-2025074249-A1 NITROGEN-LINKED BENZISOXAZOLE SULFONAMIDE DERIVATIVES FOR THE TREATMENT OF CANCER PFIZER INC. (US) 2025-04-10 WO disclosed
US-20250066570-A1 LAMINATE DEVICE WITH METALLIC AND POLYMER LAYERS QUANTUM MICROMATERIALS INC (US) 2025-02-27 US disclosed
CN-118126043-B PLK4 inhibitor with high selectivity and preparation method and application thereof 沈阳药科大学 2025-01-28 CN disclosed
CN-115925705-B Heteroaromatic derivative regulator, preparation method and application thereof 江苏豪森药业集团有限公司 2024-12-31 CN disclosed
US-20240360135-A1 IMIDAZO[1,2-B]PYRIDAZINYL COMPOUNDS AND USES THEREOF SUMITOMO PHARMA ONCOLOGY INC (US) 2024-10-31 US disclosed
WO-2002057259-A2 PYRAZOLE COMPOUNDS USEFUL AS PROTEIN KINASE INHIBITORS VERTEX PHARMACEUTICALS INCORPORATED (US) 2002-07-25 WO disclosed
WO-2002050065-A2 PYRAZOLE COMPOUNDS USEFUL AS PROTEIN KINASE INHIBITORS VERTEX PHARMACEUTICALS INCORPORATED (US) 2002-06-27 WO disclosed
WO-2002022608-A1 PYRAZOLE COMPOUNDS USEFUL AS PROTEIN KINASE INHIBITORS VERTEX PHARMACEUTICALS INCORPORATED (US) 2002-03-21 WO disclosed
WO-2000059907-A2 PYRAZOLOTRIAZINES AS CRF ANTAGONISTS DU PONT PHARMACEUTICALS COMPANY (US) 2000-10-12 WO disclosed
US-5475114-A Angiotensin-11 antagonist; therapeutical agent used for treating hypertension and chronic heart failure YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) 1995-12-12 US disclosed
EP-0646584-A1 PYRAZOLOTRIAZOLE DERIVATIVE YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) 1995-04-05 EP disclosed
CN-1069978-A Pyrazolotriazole derivatives YAMANOUCHI PHARMA CO LTD (JP) 1993-03-17 CN disclosed
US-4456668-A DYE BLEACH, TEXTILE DYES CIBA GEIGY AG (CH) 1984-06-26 US disclosed
US-4409143-A TEXTILES, PHOTOGRAPHY CIBA-GEIGY AG (CH) 1983-10-11 US disclosed
EP-0015872-A1 Cationic azodyestuffs, their preparation and their use in dyeing and printing textile material CIBA-GEIGY AG (CH) 1980-09-17 EP disclosed