Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLP1R | P43220 | 8/20 | 0.49 |
| ▸ | ALB | P02768 | 1/20 | 0.42 |
| ▸ | TLR2 | O60603 | 1/20 | 0.41 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.41 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.37 |
| ▸ | PRKACA | P17612 | 1/20 | 0.37 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19069693 | 0.84 | GLP1R (0.41) | GLP1RALBTLR2C3AR1 | |
| SCHEMBL16093004 | 0.84 | GLP1R (0.37) | GLP1RALBTLR2NOD1SIRT2 | |
| SCHEMBL27310385 | 0.81 | GLP1R (0.57) | GLP1RALBTLR2NOD1ROCK2 | |
| SCHEMBL15259287 | 0.79 | GLP1R (0.70) | GLP1RTLR2NOD1SIRT2 | |
| SCHEMBL14438806 | 0.79 | GLP1R (0.70) | GLP1RTLR2NOD1SIRT2 | |
| SCHEMBL20750924 | 0.79 | GLP1R (0.59) | GLP1R | |
| SCHEMBL14685800 | 0.78 | GLP1R (0.46) | GLP1RALB | |
| SCHEMBL45887 | 0.78 | GLP1R (0.57) | GLP1RALBTLR2NOD1SIRT2 | |
| SCHEMBL12972408 | 0.78 | GLP1R (0.49) | GLP1RALBTLR2SMN1; SMN2 | |
| SCHEMBL12147610 | 0.78 | GLP1R (0.45) | GLP1RALBTLR2ROCK2PRKACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9234192-B2 | Conjugated proteins | NOVO NORDISK A/S (DK) | 2016-01-12 | — | — | US | disclosed |
| US-9234192-B2 | Conjugated proteins | NOVO NORDISK A/S (DK) | 2016-01-12 | — | — | US | disclosed |