SCHEMBL14685800

SCHEMBL14685800

CCOCCOCC(=O)NCCOCCOCC(=O)NCCCC[C@H](NC)C(N)=O

nearest known ligand 0.46

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ GLP1R P43220 8/20 0.46
▸ EPHX2 P34913 2/20 0.38
▸ ALDH1A1 P00352 1/20 0.38
▸ TSHR P16473 2/20 0.35
▸ NAMPT P43490 1/20 0.35
▸ ALB P02768 1/20 0.34
▸ CASP1 P29466 1/20 0.34
▸ CASP7 P55210 1/20 0.34
▸ HSD17B10 Q99714 1/20 0.34
▸ L3MBTL1 Q9Y468 1/20 0.33
▸ FAAH O00519 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12807268 0.93 GLP1R (0.46) GLP1RTSHRALBFAAH
SCHEMBL14685801 0.93 GLP1R (0.48) GLP1RTSHRALBFAAH
SCHEMBL12743611 0.93 GLP1R (0.46) GLP1RTSHRALBFAAH
SCHEMBL8115663 0.90 GLP1R (0.51) GLP1RTSHRALB
SCHEMBL16257635 0.89 GLP1R (0.47) GLP1REPHX2ALDH1A1TSHRNAMPT
SCHEMBL13539399 0.87 GLP1R (0.46) GLP1RTSHRALB
SCHEMBL14685781 0.86 GLP1R (0.54) GLP1REPHX2ALDH1A1TSHRNAMPT
SCHEMBL29330971 0.86 GLP1R (0.51) GLP1REPHX2ALDH1A1TSHRNAMPT
SCHEMBL20144618 0.86 NAMPT (0.40) GLP1RALDH1A1TSHRNAMPTALB
SCHEMBL14550361 0.85 GLP1R (0.56) GLP1REPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130035285-A1 NOVEL GLUCAGON ANALOGUES NOVO NORDISK A/S (DK) 2013-02-07 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130035285-A1 NOVEL GLUCAGON ANALOGUES GLP1R, GIPR, IAPP GLP1R 1/4885EPHX2 4133/4885ALDH1A1 4564/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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