Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 20/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16640418 | 0.90 | SLC6A9 (0.61) | SLC6A9 | |
| SCHEMBL16640413 | 0.90 | SLC6A9 (0.48) | SLC6A9 | |
| SCHEMBL16640411 | 0.90 | SLC6A9 (0.61) | SLC6A9 | |
| SCHEMBL16640419 | 0.89 | SLC6A9 (0.61) | SLC6A9 | |
| SCHEMBL16640378 | 0.85 | SLC6A9 (0.62) | SLC6A9 | |
| SCHEMBL16640414 | 0.83 | SLC6A9 (0.57) | SLC6A9 | |
| SCHEMBL16640417 | 0.81 | SLC6A9 (0.59) | SLC6A9 | |
| SCHEMBL16640407 | 0.80 | SLC6A9 (0.60) | SLC6A9 | |
| SCHEMBL16640410 | 0.79 | SLC6A9 (0.60) | SLC6A9 | |
| SCHEMBL16640435 | 0.78 | SLC6A9 (0.61) | SLC6A9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3057963-B1 | PIPERAZINE DERIVATIVES AND THE USE THEREOF AS MEDICAMENT | BOEHRINGER INGELHEIM INT (DE) | 2019-06-19 | — | — | EP | disclosed |
| US-9233953-B2 | Derivatives of 4-(piperazinylcarbonyl)thiane-1, 1-dione which inhibit GlyT1 | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2016-01-12 | — | — | US | disclosed |
| US-9233953-B2 | Derivatives of 4-(piperazinylcarbonyl)thiane-1, 1-dione which inhibit GlyT1 | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2016-01-12 | — | — | US | disclosed |