SCHEMBL17424355

SCHEMBL17424355

COC(=O)c1cccc2nc(O)n(Cc3ccc(-c4ccccc4-c4noc(=O)[nH]4)cc3)c12

nearest known ligand 0.72

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
AGTR2 P50052 1/20 0.60
PPARG P37231 2/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18088504 0.89 AGTR2 (0.56) AGTR2
SCHEMBL683359 0.89 AGTR2 (0.57) AGTR2PPARG
SCHEMBL965217 0.89 AGTR2 (0.75) AGTR2PPARG
SCHEMBL15702902 0.85 AGTR2 (0.83) AGTR2PPARG
SCHEMBL13465241 0.85 AGTR2 (0.54) AGTR2PPARG
SCHEMBL683370 0.83 AGTR2 (0.61) AGTR2PPARG
SCHEMBL30849967 0.83 AGTR2 (0.67) AGTR2PPARG
SCHEMBL21083669 0.83 AGTR2 (0.67) AGTR2PPARG
SCHEMBL30539216 0.82 AGTR2 (0.82) AGTR2PPARG
SCHEMBL28653349 0.82 AGTR2 (0.82) AGTR2PPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2673274-B1 AN IMPROVED PROCESS FOR THE PREPARATION OF AZILSARTAN MEDOXOMIL JUBILANT GENERICS LTD (IN) 2019-07-17 EP disclosed
US-9233955-B2 Process for the preparation of azilsartan medoxomil JUBILANT LIFE SCIENCES, LTD. (IN) 2016-01-12 US disclosed
US-9233955-B2 Process for the preparation of azilsartan medoxomil JUBILANT LIFE SCIENCES, LTD. (IN) 2016-01-12 US disclosed