Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CREBBP | Q92793 | 2/20 | 0.49 |
| ▸ | VIM | P08670 | 1/20 | 0.48 |
| ▸ | MC4R | P32245 | 2/20 | 0.41 |
| ▸ | MC3R | P41968 | 2/20 | 0.41 |
| ▸ | MC5R | P33032 | 1/20 | 0.41 |
| ▸ | MC1R | Q01726 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12754797 | 0.94 | CREBBP (0.50) | CREBBPVIMMC4RMC3RMC5R | |
| SCHEMBL13671131 | 0.94 | CREBBP (0.51) | CREBBPVIMMC4RMC3RMC5R | |
| SCHEMBL21565404 | 0.86 | CREBBP (0.50) | CREBBPVIMMC4RMC3RMC5R | |
| SCHEMBL17424488 | 0.81 | CREBBP (0.47) | CREBBPVIMMC4RMC3RMC1R | |
| SCHEMBL17366443 | 0.81 | CREBBP (0.43) | CREBBPVIMMC4RMC3RMC5R | |
| SCHEMBL17424480 | 0.80 | CREBBP (0.40) | CREBBPVIMMC4RMC3RMC1R | |
| SCHEMBL17366444 | 0.80 | CREBBP (0.43) | CREBBPVIMMC4RMC3RMC5R | |
| SCHEMBL21376568 | 0.78 | MC4R (0.54) | CREBBPMC4RMC3RMC5RMC1R | |
| SCHEMBL21376308 | 0.78 | MC4R (0.54) | CREBBPMC4RMC3RMC5RMC1R | |
| SCHEMBL21376908 | 0.78 | MC4R (0.54) | CREBBPMC4RMC3RMC5RMC1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9233162-B2 | High affinity VEGF-receptor antagonists | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2016-01-12 | — | — | US | disclosed |
| US-9233162-B2 | High affinity VEGF-receptor antagonists | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2016-01-12 | — | — | US | disclosed |