Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 3/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | TPMT | P51580 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL668765 | 0.83 | CNR2 (0.43) | CNR2ABCB1CYP3A4 | |
| SCHEMBL9376556 | 0.76 | CNR2 (0.39) | CNR2CYP3A4 | |
| SCHEMBL27709308 | 0.72 | CYP4F2 (0.39) | CNR2CYP3A4 | |
| SCHEMBL8721674 | 0.71 | TPMT (0.42) | ABCB1CYP3A4TPMT | |
| SCHEMBL8912352 | 0.69 | CYP4F2 (0.42) | CYP3A4 | |
| SCHEMBL16142850 | 0.69 | ABCB1 (0.40) | ABCB1CYP3A4TPMT | |
| SCHEMBL13307504 | 0.69 | CA12 (0.53) | CYP3A4 | |
| Hydrochloric Acid SCHEMBL11688713 | 0.69 | TPMT (0.52) | ABCB1CYP3A4TPMT | |
| SCHEMBL4859473 | 0.68 | CA12 (0.67) | CNR2CYP3A4TPMT | |
| SCHEMBL1006734 | 0.67 | TPMT (0.54) | ABCB1TPMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2463269-B1 | Bioavailable diacylhydrazine ligands for modulating the expression of exogenous genes via an ecdysone receptor complex | INTREXON CORP (US) | 2016-09-28 | — | — | EP | disclosed |
| EP-2460786-B1 | Bioavailable diacylhydrazine ligands for modulating the expression of exogenous genes via an ecdysone receptor complex | INTREXON CORP (US) | 2016-01-13 | — | — | EP | disclosed |