Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | CPT2 | P23786 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | S1PR2 | O95136 | 5/20 | 0.31 |
| ▸ | S1PR4 | O95977 | 5/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.31 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.31 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24042407 | 0.98 | EPHX1 (0.52) | EPHX1SIGMAR1FFAR1CPT2TDP1 | |
| SCHEMBL20629328 | 0.98 | EPHX1 (0.50) | EPHX1SIGMAR1 | |
| SCHEMBL20644846 | 0.91 | EPHX1 (0.61) | EPHX1SIGMAR1FFAR1CPT2TDP1 | |
| SCHEMBL21579003 | 0.91 | EPHX1 (0.61) | EPHX1SIGMAR1FFAR1CPT2TDP1 | |
| SCHEMBL22667356 | 0.91 | EPHX1 (0.68) | EPHX1SIGMAR1S1PR2S1PR4S1PR1 | |
| SCHEMBL16705253 | 0.91 | EPHX1 (0.46) | EPHX1SIGMAR1 | |
| SCHEMBL22111696 | 0.88 | EPHX1 (0.56) | EPHX1SIGMAR1S1PR2S1PR4S1PR1 | |
| SCHEMBL21398350 | 0.86 | EPHX1 (0.61) | EPHX1S1PR2S1PR4S1PR1S1PR3 | |
| SCHEMBL22403813 | 0.84 | EPHX1 (0.56) | EPHX1S1PR2S1PR4S1PR1S1PR3 | |
| SCHEMBL19597731 | 0.84 | EPHX1 (0.50) | EPHX1SIGMAR1FFAR1CPT2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2341053-B1 | CEPHALOSPORIN HAVING CATECHOL GROUP | SHIONOGI & CO (JP) | 2016-01-13 | — | — | EP | disclosed |