Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 10/20 | 0.50 |
| ▸ | CTSG | P08311 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CMA1 | P23946 | 5/20 | 0.45 |
| ▸ | F2 | P00734 | 2/20 | 0.45 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17425135 | 1.00 | ELANE (0.50) | ELANECTSGCYP3A4CYP2C9PKM | |
| SCHEMBL10080265 | 0.94 | ELANE (0.49) | ELANECTSGCYP3A4CYP2C9PKM | |
| SCHEMBL13339327 | 0.94 | ELANE (0.49) | ELANECTSGCYP3A4CYP2C9PKM | |
| SCHEMBL13982029 | 0.88 | ALDH1A1 (0.48) | ELANECYP3A4CYP2C9PKMCYP2C19 | |
| SCHEMBL6595982 | 0.82 | DPP3 (0.51) | ELANECYP3A4CYP2C9PKMCYP2C19 | |
| SCHEMBL27598028 | 0.80 | CYP3A4 (0.58) | CYP3A4CYP2C9PKMCYP2C19ALDH1A1 | |
| SCHEMBL13036087 | 0.79 | ELANE (0.58) | ELANECMA1 | |
| SCHEMBL13339328 | 0.79 | ELANE (0.58) | ELANECMA1 | |
| SCHEMBL10571884 | 0.78 | F2 (0.46) | ELANECTSGCMA1F2FKBP1A | |
| SCHEMBL10080266 | 0.78 | ELANE (0.54) | ELANECTSGCMA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2170270-B1 | COMPOSITIONS FOR DELIVERING MEDICAMENTS INTO THE LUNGS, USES THEREOF | PAKA PULMONARY PHARMACEUTICALS INC (US) | 2016-01-13 | — | — | EP | disclosed |