SCHEMBL17425634

SCHEMBL17425634

c1ccc(-c2cccc(-c3cccc4c3oc3ccc(-c5cccc(-c6nc(-c7ccccc7)nc(-c7ccccc7)n6)c5)cc34)c2)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.49
PIM1 P11309 1/20 0.43
CSNK2A2 P19784 1/20 0.43
CSNK2B P67870 1/20 0.43
PIM3 Q86V86 1/20 0.43
PIM2 Q9P1W9 1/20 0.43
PLA2G2A P14555 4/20 0.41
PLA2G4A P47712 4/20 0.41
PLA2G10 O15496 1/20 0.41
PRKDC P78527 4/20 0.40
GGPS1 O95749 1/20 0.40
PTPRF P10586 3/20 0.39
PTPN2 P17706 3/20 0.39
PTPN1 P18031 3/20 0.39
ALDH1A1 P00352 2/20 0.39
HPGD P15428 2/20 0.39
L3MBTL1 Q9Y468 2/20 0.38
GAA P10253 1/20 0.38
PTGES2 Q9H7Z7 1/20 0.37
MAPT P10636 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24216812 1.00 ALOX5 (0.49) ALOX5PIM1CSNK2A2CSNK2BPIM3
SCHEMBL24215980 1.00 ALOX5 (0.49) ALOX5PIM1CSNK2A2CSNK2BPIM3
SCHEMBL24526096 1.00 ALOX5 (0.49) ALOX5PIM1CSNK2A2CSNK2BPIM3
SCHEMBL24526106 1.00 ALOX5 (0.49) ALOX5PIM1CSNK2A2CSNK2BPIM3
SCHEMBL17425611 1.00 ALOX5 (0.49) ALOX5PIM1CSNK2A2CSNK2BPIM3
SCHEMBL24217318 0.97 ALOX5 (0.53) ALOX5PIM1CSNK2A2CSNK2BPIM3
SCHEMBL24526104 0.97 ALOX5 (0.46) ALOX5PIM1CSNK2A2CSNK2BPIM3
SCHEMBL24526090 0.97 ALOX5 (0.46) ALOX5PIM1CSNK2A2CSNK2BPIM3
SCHEMBL24526190 0.97 ALOX5 (0.46) ALOX5PIM1CSNK2A2CSNK2BPIM3
SCHEMBL24525895 0.97 ALOX5 (0.46) ALOX5PIM1CSNK2A2CSNK2BPIM3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170054087-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2017-02-23 US disclosed
US-20160093808-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2016-03-31 US disclosed
US-20160028021-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2016-01-28 US disclosed
EP-2966706-A2 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2016-01-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160028021-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, OR10J3 ALOX5 336/4885PIM1 3027/4885CSNK2A2 3860/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.