Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | WNT3A | P56704 | 1/20 | 0.34 |
| ▸ | AXL | P30530 | 2/20 | 0.34 |
| ▸ | MET | P08581 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17427355 | 0.91 | POLB (0.48) | POLBALDH1A1LMNASMN1; SMN2KDM4E | |
| SCHEMBL16022074 | 0.81 | POLB (0.45) | POLBALDH1A1KMT2AUSP2LMNA | |
| SCHEMBL17427356 | 0.80 | POLB (0.48) | POLBALDH1A1KMT2ALMNAHTT | |
| SCHEMBL17427459 | 0.78 | POLB (0.45) | POLBALDH1A1LMNAAXLMET | |
| SCHEMBL17427463 | 0.77 | POLB (0.45) | POLBALDH1A1KMT2ALMNAHTT | |
| SCHEMBL17427351 | 0.77 | POLB (0.45) | POLBALDH1A1LMNA | |
| SCHEMBL17427467 | 0.77 | POLB (0.45) | POLBALDH1A1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL17427462 | 0.77 | POLB (0.40) | POLBLMNAHTTKDM4EMET | |
| SCHEMBL17222514 | 0.76 | POLB (0.51) | POLBALDH1A1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL16022005 | 0.76 | POLB (0.44) | POLBALDH1A1KMT2ALMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160009693-A1 | HERBICIDAL COMPOUNDS | SYNGENTA LIMITED (GB) | 2016-01-14 | — | — | US | disclosed |
| US-20160009693-A1 | HERBICIDAL COMPOUNDS | SYNGENTA LIMITED (GB) | 2016-01-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160009693-A1 | HERBICIDAL COMPOUNDS | DDT, HAX1, CYP4X1 | POLB 4093/4885ALDH1A1 79/4885KMT2A 949/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.