SCHEMBL17427690

SCHEMBL17427690

c1ccc(-c2ccc3ccc4ccc(-c5ccccn5)c5ccc2c3c45)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TGFBR1 P36897 1/20 0.44
LMNA P02545 5/20 0.42
KDM4E B2RXH2 5/20 0.42
CCR1 P32246 2/20 0.42
CCR5 P51681 2/20 0.42
CCR8 P51685 2/20 0.42
METAP1 P53582 2/20 0.42
CYP1A2 P05177 1/20 0.42
POLB P06746 1/20 0.42
BLM P54132 1/20 0.42
HIF1A Q16665 1/20 0.42
DOHH Q9BU89 1/20 0.42
P4HTM Q9NXG6 1/20 0.42
SMN1; SMN2 Q16637 6/20 0.42
RAB9A P51151 5/20 0.42
NPC1 O15118 4/20 0.42
HPGD P15428 3/20 0.42
CASP3 P42574 1/20 0.42
SENP8 Q96LD8 1/20 0.42
SENP7 Q9BQF6 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16483300 0.92 KDM4E (0.41) TGFBR1LMNAKDM4ECCR1CCR5
SCHEMBL16484830 0.92 KDM4E (0.41) TGFBR1LMNAKDM4ECCR1CCR5
SCHEMBL15077962 0.91 KDM4E (0.50) TGFBR1LMNAKDM4ECCR1CCR5
SCHEMBL16484891 0.88 SMN1; SMN2 (0.42) LMNAKDM4ECCR1CCR5CCR8
SCHEMBL16483330 0.88 SMN1; SMN2 (0.42) LMNAKDM4ECCR1CCR5CCR8
SCHEMBL16483351 0.88 KDM4E (0.41) TGFBR1LMNAKDM4ECCR1CCR5
SCHEMBL16483084 0.88 RAB9A (0.47) TGFBR1LMNAKDM4ECCR1CCR5
SCHEMBL16483047 0.88 KDM4E (0.41) TGFBR1LMNAKDM4ECCR1CCR5
SCHEMBL16483791 0.87 KDM4E (0.39) TGFBR1LMNAKDM4ECCR1CCR5
SCHEMBL16483027 0.87 KDM4E (0.39) TGFBR1LMNAKDM4ECCR1CCR5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9401484-B2 Organic light-emitting device having increased electron transport ability of an electron transport region SAMSUNG DISPLAY CO., LTD. (KR) 2016-07-26 US disclosed
US-9401484-B2 Organic light-emitting device having increased electron transport ability of an electron transport region SAMSUNG DISPLAY CO., LTD. (KR) 2016-07-26 US disclosed
US-20160013430-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2016-01-14 US disclosed
US-20160013430-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2016-01-14 US disclosed