SCHEMBL1742837

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1957290	0.90	KDM4E (0.49)	CYP1A2CYP2C9CYP2C19GAAHTT
	SCHEMBL1956942	0.89	TSHR (0.46)	CYP1A2CYP2C9CYP2C19GAAL3MBTL1
	SCHEMBL1957595	0.88	TDP1 (0.48)	CYP1A2CYP2C9CYP2C19GAAL3MBTL1
	SCHEMBL1959329	0.86	GAA (0.51)	GAAL3MBTL1TSHRSMN1; SMN2KMT2A
	SCHEMBL1958609	0.86	CA12 (0.49)	GAATSHRSMN1; SMN2KMT2ALMNA
	SCHEMBL1742275	0.86	SMN1; SMN2 (0.51)	CYP1A2CYP2C9CYP2C19GAAL3MBTL1
	SCHEMBL1958509	0.85	TSHR (0.43)	CYP1A2CYP2C9CYP2C19GAATSHR
	SCHEMBL1955771	0.84	HTR2A (0.52)	CYP1A2TSHRSLC6A2SLC6A4SLC6A3
	SCHEMBL1957320	0.83	KDM4E (0.51)	CYP1A2CYP2C9CYP2C19L3MBTL1HTT
	SCHEMBL1960348	0.83	TSHR (0.50)	CYP1A2CYP2C9CYP2C19L3MBTL1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.