SCHEMBL1955771

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5837318	0.90	HTR2A (0.52)	HTR2ASLC6A4KCNH2CYP1A2TSHR
	SCHEMBL1959407	0.89	TSHR (0.42)	HTR2ASLC6A4KCNH2CYP1A2TSHR
	SCHEMBL1960348	0.87	TSHR (0.50)	CYP1A2TSHR
	SCHEMBL1956942	0.85	TSHR (0.46)	CYP1A2TSHRCYP4F2CYP4A11
	SCHEMBL1742837	0.84	CYP1A2 (0.51)	SLC6A4CYP1A2TSHRSLC6A2SLC6A3
	SCHEMBL1957290	0.83	KDM4E (0.49)	CYP1A2TSHR
	SCHEMBL1958231	0.83	TSHR (0.47)	SLC6A4CYP1A2TSHRCYP4F2CYP4A11
	SCHEMBL2478958	0.82	TSHR (0.44)	TSHRCYP4F2CYP4A11
	SCHEMBL3498239	0.82	THRA (0.46)	—
	SCHEMBL1956268	0.82	TSHR (0.47)	SLC6A4TSHRCYP4F2CYP4A11SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.