Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20462363 | 0.82 | — | — | |
| SCHEMBL16404737 | 0.73 | — | — | |
| SCHEMBL20094640 | 0.72 | — | — | |
| SCHEMBL12809902 | 0.69 | — | — | |
| SCHEMBL13896904 | 0.69 | — | — | |
| SCHEMBL14878332 | 0.68 | ALDH1A1 (0.31) | — | |
| SCHEMBL18698208 | 0.67 | — | — | |
| SCHEMBL14043354 | 0.67 | TSHR (0.39) | TSHR | |
| SCHEMBL8923525 | 0.66 | — | — | |
| SCHEMBL15108815 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016007534-A1 | THERAPEUTIC COMPOUNDS AND METHODS OF USE THEREOF | GENENTECH, INC. (US) | 2016-01-14 | — | — | WO | disclosed |