Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6894966 | 1.00 | PTGS1 (0.34) | PTGS1CTSKNR1I2PGRADORA3 | |
| SCHEMBL6898513 | 0.95 | PTGS1 (0.41) | PTGS1CTSKNR1I2PGRADORA3 | |
| SCHEMBL6897264 | 0.95 | PTGS1 (0.41) | PTGS1CTSKNR1I2PGRADORA3 | |
| SCHEMBL6896707 | 0.85 | PTGS1 (0.34) | PTGS1NR1I2PGRADORA3PTGS2 | |
| SCHEMBL6894713 | 0.85 | PTGS1 (0.34) | PTGS1NR1I2PGRADORA3PTGS2 | |
| SCHEMBL14899323 | 0.85 | PTGS1 (0.36) | PTGS1NR1I2PGRADORA3PTGS2 | |
| SCHEMBL6897334 | 0.81 | PTGS1 (0.41) | PTGS1NR1I2PGRADORA3PTGS2 | |
| SCHEMBL12415217 | 0.81 | PTGS1 (0.41) | PTGS1NR1I2PGRADORA3PTGS2 | |
| SCHEMBL12513931 | 0.80 | PTGS1 (0.44) | PTGS1NR1I2PGRADORA3PTGS2 | |
| SCHEMBL14775231 | 0.80 | ALDH1A1 (0.46) | PTGS1NR1I2PGRADORA3PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9580417-B2 | Prodrugs of heteraromatic compounds | ALKERMES PHARMA IRELAND LIMITED (IE) | 2017-02-28 | — | — | US | disclosed |
| US-20160009713-A1 | Prodrugs of Heteraromatic Compounds | JPMORGAN CHASE BANK, N.A. AS ADMINISTRATIVE AGENT | 2016-01-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160009713-A1 | Prodrugs of Heteraromatic Compounds | CYP2D6, CYP2B6, CYP3A4 | PTGS1 1120/4885CTSK 1582/4885NR1I2 392/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.