Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 16/20 | 0.48 |
| ▸ | DPP7 | Q9UHL4 | 6/20 | 0.48 |
| ▸ | DPP8 | Q6V1X1 | 5/20 | 0.48 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.46 |
| ▸ | PREP | P48147 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL713852 | 0.73 | DPP4 (0.54) | DPP4DPP7DPP8DPP9PREP | |
| SCHEMBL6294602 | 0.72 | PREP (0.52) | DPP4DPP8DPP9PREP | |
| SCHEMBL6202306 | 0.69 | DPP4 (0.63) | DPP4DPP7DPP8DPP9 | |
| SCHEMBL15130351 | 0.69 | DPP4 (0.79) | DPP4DPP7DPP8DPP9 | |
| SCHEMBL13034928 | 0.69 | DPP4 (0.79) | DPP4DPP7DPP8DPP9 | |
| SCHEMBL712816 | 0.68 | DPP4 (0.59) | DPP4DPP7DPP8DPP9PREP | |
| SCHEMBL12051045 | 0.67 | DPP4 (0.70) | DPP4DPP7DPP8DPP9PREP | |
| SCHEMBL3604552 | 0.67 | DPP4 (0.65) | DPP4DPP7DPP8DPP9PREP | |
| SCHEMBL14392760 | 0.67 | DPP4 (1.00) | DPP4DPP7DPP8DPP9 | |
| SCHEMBL15636202 | 0.67 | DPP4 (1.00) | DPP4DPP7DPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2389176-A1 | NOVEL METABOLIC DISEASE THERAPY | The University Of Sydney (AU) | 2011-11-30 | — | — | EP | claimed |
| US-20110253961-A1 | Combined Guardrail and Cable Safety Systems | TRINITY INDUSTRIES, INC. (US) | 2011-10-20 | — | — | US | claimed |
| WO-2010083570-A1 | NOVEL METABOLIC DISEASE THERAPY | THE UNIVERSITY OF SYDNEY (AU) | 2010-07-29 | — | — | WO | claimed |