⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphine SCHEMBL18110397 | 0.98 | — | — | |
| Hydrochloric Acid SCHEMBL2076896 | 0.98 | — | — | |
| Bromide SCHEMBL4240042 | 0.98 | — | — | |
| Hydrochloric Acid SCHEMBL18044 | 0.98 | — | — | |
| Ammonia Solution, Strong SCHEMBL28235189 | 0.98 | — | — | |
| Hydrochloric Acid SCHEMBL2239040 | 0.95 | CYP1A2 (0.54) | — | |
| Hypochlorous Acid SCHEMBL7837490 | 0.95 | CYP1A2 (0.54) | — | |
| Ammonia Solution, Strong SCHEMBL28235191 | 0.95 | CHRNB2 (0.55) | — | |
| Hydrochloric Acid SCHEMBL17284874 | 0.89 | CYP1A2 (0.48) | — | |
| Acetonitrile SCHEMBL28026103 | 0.88 | CHRNB2 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2600 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12281094-B2 | Preparation method of racemic nicotine | SHENZHEN ZINWI BIO-TECH CO., LTD (CN) | 2025-04-22 | — | — | US | claimed |
| CN-119264298-A | Preparation method of antibacterial and antioxidant phenolic chitosan biquaternary ammonium salt | 安康学院 | 2025-01-07 | — | — | CN | claimed |
| CN-118956069-A | Polyvinyl chloride cable material and preparation method thereof | 惠州乐庭智联科技股份有限公司 | 2024-11-15 | — | — | CN | claimed |
| EP-4151629-B1 | METHOD FOR PREPARING RACEMIC NICOTINE | SHENZHEN ZINWI BIO TECH CO LTD (CN) | 2024-10-23 | — | — | EP | claimed |
| CN-117285437-B | Bexarotene derivative, preparation method and application thereof, and anti-tumor drug | 沈阳药科大学 | 2024-09-17 | — | — | CN | claimed |
| CN-117624140-A | CXCR4 antagonists, methods of making and uses thereof | 杭州师范大学 | 2024-03-01 | — | — | CN | claimed |
| CN-117582379-A | Method for promoting dissolution and enhancing synergy of cosmetic and medical raw materials | 上海湃肽生物科技有限公司 | 2024-02-23 | — | — | CN | claimed |
| CN-114702475-B | Synthesis process of nicotine with single configuration | 大连天源基化学有限公司 | 2023-12-26 | — | — | CN | claimed |
| WO-2023221862-A1 | ANTI-PARASITIC INFECTION EXTERNAL PHARMACEUTICAL FORMULATION, PREPARATION METHOD THEREFOR AND USE THEREOF | 天津瑞普生物技术股份有限公司 | 2023-11-23 | — | — | WO | claimed |
| WO-2023221854-A1 | ANTI-PARASITIC INFECTION ORAL PHARMACEUTICAL PREPARATION, METHOD FOR PREPARING SAME, AND USE THEREOF | 天津瑞普生物技术股份有限公司 | 2023-11-23 | — | — | WO | claimed |
| WO-1998009978-A1 | 6-O-SUBSTITUTED KETOLIDES HAVING ANTIBACTERIAL ACTIVITY | ABBOTT LABORATORIES (US) | 1998-03-12 | — | — | WO | claimed |
| US-5717097-A | N-(2(R)-HYDROXY-1(S)-INDANYL)-2(R)-PHENYLMETHYL-4(S)-(HYDROXY) -5-SUBSTITUTED-N'-(T-BUTYLCARBAMOYL)PIPERAZINYL))PENTANEAMIDE COMPOUNDS | MERCK & CO., INC. (US) | 1998-02-10 | — | — | US | claimed |
| WO-1997042204-A1 | 6-O-SUBSTITUTED ERYTHROMYCINS AND METHOD FOR MAKING THEM | ABBOTT LABORATORIES (US) | 1997-11-13 | — | — | WO | claimed |
| US-5475112-A | Reducing a substituted trichloromethylpyridine derivative in presence of a proton donor and solvent | ISHIHARA SANGYO KAISHA LTD. (JP) | 1995-12-12 | — | — | US | claimed |
| EP-0482342-A2 | Hypocholesterolemic unsymmetrical dithiol ketals | Bristol-Myers Squibb Company (US) | 1992-04-29 | — | — | EP | claimed |
| US-5084459-A | Insecticides | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-01-28 | — | — | US | claimed |
| EP-0366085-A2 | Tetrahydropyrimidines, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1990-05-02 | — | — | EP | claimed |
| US-4778896-A | Process for the preparation of 5-chloromethylpyridines | BAYER AKTIENGESELLSCHAFT (DE) | 1988-10-18 | — | — | US | claimed |
| US-4435575-A | Process for preparing carboxylated organic compounds | MONTEDISON S.P.A. (IT) | 1984-03-06 | — | — | US | claimed |
| EP-0053681-A1 | B-Nicotinoyloxyethyl nicotinic S-acid ester and its preparation via 2-Mercaptoethyl nicotinate | Tauro, Celesio Sonnino (IT) | 1982-06-16 | — | — | EP | claimed |