SCHEMBL17433115

SCHEMBL17433115

c1ccc2c(c1)oc1c(-c3ccc(-n4c5ccccc5c5ccc6c(ccc7oc8ccccc8c76)c54)cc3)cccc12

nearest known ligand 0.43

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.43
PRKDC P78527 5/20 0.38
GGPS1 O95749 1/20 0.34
CDC14B O60729 2/20 0.32
CDC14A Q9UNH5 2/20 0.32
PIK3CD O00329 1/20 0.32
PIK3CB P42338 1/20 0.32
ATM Q13315 2/20 0.32
KDM4E B2RXH2 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
PTGES2 Q9H7Z7 1/20 0.32
CDC25A P30304 1/20 0.31
CDC25B P30305 1/20 0.31
CDC25C P30307 1/20 0.31
DUSP3 P51452 1/20 0.31
ADK P55263 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24923248 0.93 ALOX5 (0.43) ALOX5PRKDCGGPS1CDC14BCDC14A
SCHEMBL17381097 0.93 ALOX5 (0.43) ALOX5PRKDCGGPS1CDC14BCDC14A
SCHEMBL15759597 0.89 ALOX5 (0.48) ALOX5PRKDCGGPS1PIK3CDPIK3CB
SCHEMBL17246076 0.88 ALOX5 (0.40) ALOX5PRKDCGGPS1CDC14BCDC14A
SCHEMBL17690925 0.88 ALOX5 (0.47) ALOX5PRKDCGGPS1PIK3CDPIK3CB
SCHEMBL15759609 0.88 ALOX5 (0.47) ALOX5PRKDCGGPS1PIK3CDPIK3CB
SCHEMBL14208828 0.88 ALOX5 (0.47) ALOX5PRKDCGGPS1PIK3CDPIK3CB
SCHEMBL17433155 0.88 ALOX5 (0.41) ALOX5PRKDCGGPS1CDC14BCDC14A
SCHEMBL18926337 0.88 ALOX5 (0.41) ALOX5PRKDCGGPS1CDC14BCDC14A
SCHEMBL24812042 0.87 ALOX5 (0.39) ALOX5PRKDCGGPS1CDC14BCDC14A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9806271-B2 Organic electroluminescent compound and organic electroluminescent device comprising the same ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2017-10-31 US disclosed
US-9806271-B2 Organic electroluminescent compound and organic electroluminescent device comprising the same ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2017-10-31 US disclosed
US-20170162797-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD (KR) 2017-06-08 US disclosed
US-20170162797-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD (KR) 2017-06-08 US disclosed
WO-2016006959-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2016-01-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170162797-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME L1CAM, CHRM1, OR10J3 ALOX5 1416/4885PRKDC 4337/4885GGPS1 2106/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.