⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8960613 | 0.77 | — | — | |
| SCHEMBL8847277 | 0.71 | PTPN7 (0.40) | — | |
| SCHEMBL8960458 | 0.68 | — | — | |
| SCHEMBL25005935 | 0.68 | — | — | |
| SCHEMBL233379 | 0.67 | — | — | |
| SCHEMBL8388785 | 0.65 | — | — | |
| SCHEMBL1961299 | 0.65 | — | — | |
| SCHEMBL28162082 | 0.65 | LMNA (0.32) | — | |
| SCHEMBL8960922 | 0.65 | — | — | |
| SCHEMBL1897706 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170216282-A1 | Compounds, Formulations, and Methods for Treating or Preventing Inflammatory Skin Disorders | GALDERMA LABORATORIES INC | 2017-08-03 | — | — | US | disclosed |
| US-20150202202-A1 | COMPOUNDS, FORMULATIONS, AND METHODS FOR TREATING OR PREVENTING INFLAMMATORY SKIN DISORDERS | Galderma Laboratories, L.P. (US) | 2015-07-23 | — | — | US | disclosed |
| US-8993571-B2 | Compounds, formulations, and methods for treating or preventing inflammatory skin disorders | Galderma Laboratories, L.P. (US) | 2015-03-31 | — | — | US | disclosed |
| EP-2815748-A1 | Compounds, formulations, and methods for treating or preventing rosacea | Galderma Pharma S.A. (CH) | 2014-12-24 | — | — | EP | disclosed |
| US-8859551-B2 | Compounds, formulations, and methods for treating or preventing inflammatory skin disorders | GALDERMA LABORATORIES INC. (US) | 2014-10-14 | — | — | US | disclosed |
| US-8557817-B2 | Compounds, formulations, and methods for treating or preventing inflammatory skin disorders | GALDERMA LABORATORIES INC. (US) | 2013-10-15 | — | — | US | disclosed |
| US-20130172358-A1 | Compounds, Formulations, and Methods for Treating or Preventing Inflammatory Skin Disorders | GALDERMA LABORATORIES INC. (US) | 2013-07-04 | — | — | US | disclosed |
| US-20130172359-A1 | Compounds, Formulations, and Methods for Treating or Preventing Inflammatory Skin Disorders | GALDERMA LABORATORIES INC. (US) | 2013-07-04 | — | — | US | disclosed |
| EP-1761266-B1 | COMPOUNDS, FORMULATIONS, AND METHODS FOR TREATING OR PREVENTING INFLAMMATORY SKIN DISORDERS | GALDERMA PHARMA SA (CH) | 2013-05-08 | — | — | EP | disclosed |
| US-20120277241-A1 | Compounds, Formulations, and Methods for Treating or Preventing Inflammatory Skin Disorders | GALDERMA LABORATORIES, INC. (US) | 2012-11-01 | — | — | US | disclosed |
| EP-2481412-A1 | Compounds, formulations, and methods for treating or preventing inflammatory skin disorders | Galderma Pharma S.A. (CH) | 2012-08-01 | — | — | EP | disclosed |
| EP-2388007-A1 | Compounds, formulations, and methods for treating or preventing rosacea | Galderma Pharma S.A. (CH) | 2011-11-23 | — | — | EP | disclosed |
| EP-1631293-B1 | COMPOUNDS, FORMULATIONS, AND METHODS FOR TREATING OR PREVENTING ROSACEA | GALDERMA PHARMA SA (CH) | 2011-10-26 | — | — | EP | disclosed |
| US-8038451-B2 | Multi-board printed circuit assembly having aligned connectors | HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) | 2011-10-18 | — | — | US | disclosed |
| US-7439241-B2 | Compounds, formulations, and methods for treating or preventing rosacea | GALDERMA LABORATORIES, INC. (US) | 2008-10-21 | — | — | US | disclosed |
| US-20060171974-A1 | Compounds, formulations, and methods for treating or preventing rosacea | GALDERMA LABORATORIES INC. | 2006-08-03 | — | — | US | disclosed |
| US-20050276830-A1 | Compounds, formulations, and methods for treating or preventing inflammatory skin disorders | GALDERMA LABORATORIES INC. | 2005-12-15 | — | — | US | disclosed |
| US-20040242588-A1 | Compounds, formulations, and methods for treating or preventing rosacea | Galderma Holding SA (CH) | 2004-12-02 | — | — | US | disclosed |
| US-6369052-B1 | REVERSE NEURONAL DYSFUNCTION; ALZHEIMER'S; PARKINSON'S DISEASE; AMYOTROPHIC LATERAL SCLEROSIS; STROKES; SPINAL-CORD AND PERIPHERAL NERVE INJURIES; TRANSDERMAL PATCH. | GEORGETOWN UNIVERSITY | 2002-04-09 | — | — | US | disclosed |