Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 20/20 | 0.53 |
| ▸ | CDC37 | Q16543 | 1/20 | 0.52 |
| ▸ | HSP90AB1 | P08238 | 9/20 | 0.48 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4991999 | 0.86 | HSP90AA1 (0.50) | HSP90AA1CDC37 | |
| SCHEMBL4142204 | 0.86 | HSP90AA1 (0.50) | HSP90AA1CDC37 | |
| SCHEMBL4896589 | 0.86 | HSP90AA1 (0.52) | HSP90AA1CDC37HSP90AB1 | |
| SCHEMBL1744449 | 0.86 | HSP90AA1 (0.57) | HSP90AA1CDC37 | |
| SCHEMBL4146277 | 0.84 | HSP90AA1 (0.53) | HSP90AA1CDC37 | |
| SCHEMBL4997714 | 0.84 | HSP90AA1 (0.54) | HSP90AA1CDC37HSP90AB1 | |
| SCHEMBL2441832 | 0.84 | HSP90AA1 (0.52) | HSP90AA1CDC37HSP90AB1 | |
| SCHEMBL1858420 | 0.81 | HSP90AA1 (0.50) | HSP90AA1HSP90AB1ERBB2 | |
| SCHEMBL1745214 | 0.80 | HSP90AA1 (0.52) | HSP90AA1CDC37 | |
| SCHEMBL4139744 | 0.75 | HSP90AA1 (0.52) | HSP90AA1CDC37HSP90AB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4305098-A1 | USE OF AT LEAST ONE SULFUR-CONTAINING AMINO ACID FOR STABILIZING RECYCLED THERMOPLASTICS, STABILIZED RECYCLED THERMOPLASTIC, STABILIZER COMPOSITION, MASTERBATCH, AND MOLDING COMPOUND OR MOLDED PART | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) | 2024-01-17 | — | — | EP | disclosed |
| US-20230192687-A1 | FUSED AMINO PYRIDINE AS HSP90 INHIBITORS | CURIS INC (US) | 2023-06-22 | — | — | US | disclosed |
| US-11560377-B2 | Fused amino pyridine as HSP90 inhibitors | Guris, Inc. (US) | 2023-01-24 | — | — | US | disclosed |
| US-20210292317-A1 | FUSED AMINO PYRIDINE AS HSP90 INHIBITORS | CURIS INC (US) | 2021-09-23 | — | — | US | disclosed |
| US-10844056-B2 | Fused amino pyridine as HSP90 inhibitors | CURIS, INC. (US) | 2020-11-24 | — | — | US | disclosed |
| US-20200062754-A1 | FUSED AMINO PYRIDINE AS HSP90 INHIBITORS | CURIS INC (US) | 2020-02-27 | — | — | US | disclosed |
| US-10428068-B2 | Fused amino pyridine as HSP90 inhibitors | CURIS, INC. (US) | 2019-10-01 | — | — | US | disclosed |
| US-20190010152-A1 | FUSED AMINO PYRIDINE AS HSP90 INHIBITORS | CURIS INC (US) | 2019-01-10 | — | — | US | disclosed |
| US-10035797-B2 | Fused amino pyridine as HSP90 inhibitors | CURIS, INC. (US) | 2018-07-31 | — | — | US | disclosed |
| US-20170267674-A1 | FUSED AMINO PYRIDINE AS HSP90 INHIBITORS | CURIS INC (US) | 2017-09-21 | — | — | US | disclosed |
| US-20100184801-A1 | FUSED AMINO PYRIDINES FOR THE TREATMENT OF BRAIN TUMORS | CURIS, INC. | 2010-07-22 | — | — | US | disclosed |
| EP-2069324-A1 | FUSED AMINO PYRIDINE AS HSP90 INHIBITORS | Curis, Inc. (US) | 2009-06-17 | — | — | EP | disclosed |
| US-20090093572-A1 | Stabilizer mixtures | GUGUMUS FRANCOIS | 2009-04-09 | — | — | US | disclosed |
| US-20080234297-A1 | HSP90 Inhibitors Containing a Zinc Binding Moiety | CURIS, INC. | 2008-09-25 | — | — | US | disclosed |
| WO-2008115719-A1 | FUSED AMINO PYRIDINE AS HSP90 INHIBITORS | CURIS, INC. (US) | 2008-09-25 | — | — | WO | disclosed |
| WO-2008115262-A2 | HSP90 INHIBITORS CONTAINING A ZINC BINDING MOIETY | CURIS, INC. (US) | 2008-09-25 | — | — | WO | disclosed |
| US-20080234314-A1 | FUSED AMINO PYRIDINE AS HSP90 INHIBITORS | CURIS, INC. | 2008-09-25 | — | — | US | disclosed |
| US-20080221132-A1 | Multi-Functional Small Molecules as Anti-Proliferative Agents | CURIS, INC. | 2008-09-11 | — | — | US | disclosed |
| US-6346630-B1 | 3-Arylbenzofuranones as stabilizers | CIBA SPECIALTY CHEMICALS CORPORATION | 2002-02-12 | — | — | US | disclosed |
| US-5574085-A | TO PREVENT OXIDATIVE CROSSLINKING, STORAGE, STERICALLY HINDERED ALKYLTHIOALKYLPHENOL ESTERS | CIBA-GEIGY CORPORATION (US) | 1996-11-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (13 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080221132-A1 | Multi-Functional Small Molecules as Anti-Proliferative Agents | HDAC1, HDAC6, HDAC5 | HSP90AA1 417/4885CDC37 269/4885HSP90AB1 157/4885 |
| US-20080234297-A1 | HSP90 Inhibitors Containing a Zinc Binding Moiety | HSP90AB1, HSP90AB2P, HSP90B1 | HSP90AA1 4/4885CDC37 9/4885HSP90AB1 1/4885 |
| US-20190010152-A1 | FUSED AMINO PYRIDINE AS HSP90 INHIBITORS | HSP90B1, HSP90AB1, HSP90AB2P | HSP90AA1 4/4885CDC37 5/4885HSP90AB1 2/4885 |
| US-10428068-B2 | Fused amino pyridine as HSP90 inhibitors | HSP90B1, HSP90AB1, HSP90AB2P | HSP90AA1 4/4885CDC37 5/4885HSP90AB1 2/4885 |
| US-20170267674-A1 | FUSED AMINO PYRIDINE AS HSP90 INHIBITORS | HSP90B1, HSP90AB1, HSP90AB2P | HSP90AA1 4/4885CDC37 5/4885HSP90AB1 2/4885 |
| US-20230192687-A1 | FUSED AMINO PYRIDINE AS HSP90 INHIBITORS | HSP90B1, HSP90AB1, HSP90AB2P | HSP90AA1 4/4885CDC37 5/4885HSP90AB1 2/4885 |
| US-20080234314-A1 | FUSED AMINO PYRIDINE AS HSP90 INHIBITORS | HSP90B1, HSP90AB1, HSP90AB2P | HSP90AA1 4/4885CDC37 5/4885HSP90AB1 2/4885 |
| US-20100184801-A1 | FUSED AMINO PYRIDINES FOR THE TREATMENT OF BRAIN TUMORS | IDH2, IDH1, AADAT | HSP90AA1 4349/4885CDC37 3387/4885HSP90AB1 4359/4885 |
| US-20210292317-A1 | FUSED AMINO PYRIDINE AS HSP90 INHIBITORS | HSP90B1, HSP90AB1, HSP90AB2P | HSP90AA1 4/4885CDC37 5/4885HSP90AB1 2/4885 |
| US-20200062754-A1 | FUSED AMINO PYRIDINE AS HSP90 INHIBITORS | HSP90B1, HSP90AB1, HSP90AB2P | HSP90AA1 4/4885CDC37 5/4885HSP90AB1 2/4885 |
| US-11560377-B2 | Fused amino pyridine as HSP90 inhibitors | HSP90B1, HSP90AB1, HSP90AB2P | HSP90AA1 4/4885CDC37 5/4885HSP90AB1 2/4885 |
| US-10844056-B2 | Fused amino pyridine as HSP90 inhibitors | HSP90B1, HSP90AB1, HSP90AB2P | HSP90AA1 4/4885CDC37 5/4885HSP90AB1 2/4885 |
| US-10035797-B2 | Fused amino pyridine as HSP90 inhibitors | HSP90B1, HSP90AB1, HSP90AB2P | HSP90AA1 4/4885CDC37 5/4885HSP90AB1 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.