Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP2 | O95551 | 10/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | USP2 | O75604 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | HPN | P05981 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | THRB | P10828 | 1/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.58 |
| ▸ | PDE4A | P27815 | 1/20 | 0.58 |
| ▸ | KDR | P35968 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20886849 | 0.78 | TDP2 (0.64) | TDP2MAPTCASP3CASP7CASP9 | |
| SCHEMBL22904178 | 0.78 | TDP2 (0.64) | TDP2MEN1KMT2ACASP3CASP7 | |
| SCHEMBL11565330 | 0.78 | TDP2 (0.64) | TDP2CASP3CASP7CASP9CASP6 | |
| SCHEMBL22904158 | 0.78 | TDP2 (0.64) | TDP2CASP3CASP7CASP9CASP6 | |
| SCHEMBL18010796 | 0.78 | TDP2 (1.00) | TDP2CASP3CASP7CASP9CASP6 | |
| SCHEMBL22904362 | 0.77 | TDP2 (0.58) | TDP2MEN1USP2ALDH1A1HPN | |
| SCHEMBL4411843 | 0.77 | AHR (0.61) | TDP2MEN1USP2ALDH1A1HPN | |
| SCHEMBL22904137 | 0.76 | AURKA (0.62) | TDP2CASP3CASP7CASP9CASP6 | |
| SCHEMBL18010805 | 0.75 | TDP2 (1.00) | TDP2CYP3A4CASP3CASP7CASP9 | |
| Anthralin SCHEMBL3197 | 0.74 | MAPT (1.00) | MEN1USP2ALDH1A1HPNCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021011631-A1 | FUSED-GLUTARIMIDE CRBN LIGANDS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2021-01-21 | — | — | WO | disclosed |
| EP-2975026-A1 | Method of nitrosation of organic compound | DSM Fine Chemicals Austria Nfg GmbH & Co KG (AT) | 2016-01-20 | — | — | EP | disclosed |