SCHEMBL1743535

SCHEMBL1743535

C=CC(=O)OCCC[SiH]([SiH3])O[Si](C)(C)C.C[Si](C)(C)O[SiH3].C[Si](C)(C)O[SiH3]

nearest known ligand 0.47

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.47
HPGD P15428 1/20 0.47
ALDH1A1 P00352 4/20 0.47
CYP3A4 P08684 2/20 0.47
TP53 P04637 3/20 0.40
HIF1A Q16665 3/20 0.40
HSD17B10 Q99714 1/20 0.40
THRB P10828 2/20 0.35
ATM Q13315 1/20 0.32
MAPK1 P28482 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1632851 0.81 TSHR (0.44) TSHRALDH1A1THRB
SCHEMBL4849695 0.78 TSHR (0.53) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL344380 0.75 TSHR (0.58) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL1741816 0.74 TSHR (0.57) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL19178200 0.74 TSHR (0.39) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL11442386 0.74 TSHR (0.56) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL3376502 0.73 TSHR (0.55) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL6691949 0.73 TSHR (0.50) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL6908183 0.72 TSHR (0.46) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL1585542 0.72 TSHR (0.63) TSHRHPGDALDH1A1CYP3A4TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2388119-B1 An imprint lithography process CANON NANOTECHNOLOGIES INC (US) 2016-09-07 EP disclosed
US-8318066-B2 Step and repeat imprint lithography process MOLECULAR IMPRINTS, INC. (US) 2012-11-27 US disclosed
EP-2388119-A1 An imprint lithography process Molecular Imprints, Inc. (US) 2011-11-23 EP disclosed
US-20110252704-A1 FABRICATED CULTIVATION BOX AND FABRICATED LANDSCAPE ARCHITECTURE SYSTEM CHO HEUNG-YEUL 2011-10-20 US disclosed
US-8021594-B2 Preserving filled features when vacuum wiping MOLECULAR IMPRINTS, INC. (US) 2011-09-20 US disclosed
US-20110221095-A1 Step and Repeat Imprint Lithography Process MOLECULAR IMPRINTS, INC. (US) 2011-09-15 US disclosed
US-7943081-B2 Step and repeat imprint lithography processes MOLECULAR IMPRINTS, INC. (US) 2011-05-17 US disclosed
US-20100201042-A1 Step and Repeat Imprint Lithography Processes MOLECULAR IMPRINTS, INC. (US) 2010-08-12 US disclosed
US-7727453-B2 Step and repeat imprint lithography processes MOLECULAR IMPRINTS, INC. (US) 2010-06-01 US disclosed
US-20100053578-A1 Apparatus for imprint lithography using an electric field MOLECULAR IMPRINTS, INC. (US) 2010-03-04 US disclosed
US-6900881-B2 Step and repeat imprint lithography systems MOLECULAR IMPRINTS, INC. (US) 2005-05-31 US disclosed
US-20040124566-A1 Step and repeat imprint lithography processes CITIBANK, N.A. 2004-07-01 US disclosed
WO-2004016406-A1 IMPRINT LITHOGRAPHY PROCESSES AND SYSTEMS MOLECULAR IMPRINTS, INC. (US) 2004-02-26 WO disclosed
WO-2004013693-A2 SCATTEROMETRY ALIGNMENT FOR IMPRINT LITHOGRAPHY MOLECULAR IMPRINTS, INC. (US) 2004-02-12 WO disclosed
US-20040021866-A1 Scatterometry alignment for imprint lithography CITIBANK, N.A. 2004-02-05 US disclosed
US-20040022888-A1 Alignment systems for imprint lithography CITIBANK, N.A. 2004-02-05 US disclosed
US-20040021254-A1 Alignment methods for imprint lithography CITIBANK, N.A. 2004-02-05 US disclosed
US-20040007799-A1 Formation of discontinuous films during an imprint lithography process CITIBANK, N.A. 2004-01-15 US disclosed
US-20040008334-A1 Step and repeat imprint lithography systems CITIBANK, N.A. 2004-01-15 US disclosed
US-20040009673-A1 Method and system for imprint lithography using an electric field MOLECULAR IMPRINTS, INC. 2004-01-15 US disclosed