Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 3/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6691949 | 0.89 | TSHR (0.50) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL332090 | 0.86 | TSHR (0.59) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL374776 | 0.84 | TSHR (0.57) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL7508187 | 0.84 | TSHR (0.57) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL81411 | 0.84 | TSHR (0.57) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL14175495 | 0.83 | TSHR (0.55) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL308812 | 0.82 | TSHR (0.63) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL26187833 | 0.82 | TSHR (0.63) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL10538686 | 0.81 | ATM (0.43) | TSHRALDH1A1CYP3A4HPGDATM | |
| SCHEMBL7511191 | 0.81 | TSHR (0.53) | TSHRALDH1A1CYP3A4HPGDTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2477487-A2 | AQUEOUS DISPERSIONS CONTAINING ANTIMICROBIALS IN A HYBRID NETWORK | BASF SE (DE) | 2012-07-25 | — | — | EP | claimed |
| EP-2477487-A2 | AQUEOUS DISPERSIONS CONTAINING ANTIMICROBIALS IN A HYBRID NETWORK | BASF SE (DE) | 2012-07-25 | — | — | EP | disclosed |
| WO-2010049316-A1 | COMPOSITION CONTAINING ANTIMICROBIALS IN A HYBRID NETWORK | BASF SE (DE) | 2010-05-06 | — | — | WO | disclosed |
| US-20060105047-A1 | Novel prepolymers useful in biomedical devices | BAUSCH & LOMB INCORPORATED (US) | 2006-05-18 | — | — | US | disclosed |
| US-20050100579-A1 | Novel prepolymers useful in biomedical devices | BAUSCH & LOMB INCORPORATED (US) | 2005-05-12 | — | — | US | disclosed |
| US-20030157141-A1 | Novel prepolymers useful in biomedical devices | BAUSCH & LOMB INCORPORATED (US) | 2003-08-21 | — | — | US | disclosed |
| US-6596294-B2 | Oxygen permeability and superior physical properties, contact lenses | BAUSCH & LOMB INCORPORATED | 2003-07-22 | — | — | US | disclosed |
| US-20020037271-A1 | Novel prepolymers useful in biomedical devices | BAUSCH & LOMB INCORPORATED | 2002-03-28 | — | — | US | disclosed |
| EP-0219312-B1 | Improved fluorine containing polymeric compositions useful in contact lenses | POLYMER TECHNOLOGY CORP (US) | 1995-12-20 | — | — | EP | disclosed |
| EP-0424099-B1 | Method of Preparing Polymeric Compositions for Oxygen Permeable Contact Lenses | POLYMER TECHNOLOGY CORP (US) | 1995-10-04 | — | — | EP | disclosed |
| EP-0559828-A1 | HARD SEGMENT SIZE CONTROL IN POLYURETHANE FORMATION. | BAUSCH & LOMB (US) | 1993-09-15 | — | — | EP | disclosed |
| US-5177168-A | Copolymer of an unsaturated carboxylic acid ester | POLYMER TECHNOLOGY CORP. (US) | 1993-01-05 | — | — | US | disclosed |
| US-5128434-A | Contact lenses | BAUSCH & LOMB INCORPORATED (US) | 1992-07-07 | — | — | US | disclosed |
| WO-1992009646-A1 | HARD SEGMENT SIZE CONTROL IN POLYURETHANE FORMATION | BAUSCH & LOMB INCORPORATED (US) | 1992-06-11 | — | — | WO | disclosed |
| EP-0424099-A2 | Method of Preparing Polymeric Compositions for Oxygen Permeable Contact Lenses | POLYMER TECHNOLOGY CORPORATION (US) | 1991-04-24 | — | — | EP | disclosed |
| US-4996275-A | With silicon group-substituted addition polymers; oxygen permeability, hydrophilic, deposit resistance | POLYMER TECHNOLOGY CORPORATION (US) | 1991-02-26 | — | — | US | disclosed |
| EP-0401990-A2 | Prepolymers useful in biomedical devices | BAUSCH & LOMB INCORPORATED (US) | 1990-12-12 | — | — | EP | disclosed |
| US-4861807-A | Radiation-crosslinkable compositions | WACKER-CHEMIE GMBH (DE) | 1989-08-29 | — | — | US | disclosed |
| US-4686267-A | Fluorine containing polymeric compositions useful in contact lenses | POLYMER TECHNOLOGY CORPORATION (US) | 1987-08-11 | — | — | US | disclosed |
| EP-0219312-A2 | Improved fluorine containing polymeric compositions useful in contact lenses | POLYMER TECHNOLOGY CORPORATION (US) | 1987-04-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020037271-A1 | Novel prepolymers useful in biomedical devices | TMEM63A, ECPAS, COL2A1 | TSHR 4883/4885ALDH1A1 2362/4885CYP3A4 3268/4885 |
| US-20060105047-A1 | Novel prepolymers useful in biomedical devices | TMEM63A, ECPAS, COL2A1 | TSHR 4883/4885ALDH1A1 2362/4885CYP3A4 3268/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.