Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Diethylamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Diethylamine SCHEMBL17435827 | 0.81 | CA1 (0.41) | TP53LMNAHPGDHIF1AHSD17B10 | |
| Ethylamine SCHEMBL28100555 | 0.79 | FAAH (0.31) | — | |
| Diethylamine SCHEMBL28036925 | 0.79 | TP53 (0.50) | TP53LMNAHPGDHIF1AHSD17B10 | |
| Diethylamine SCHEMBL17435863 | 0.78 | CA1 (0.33) | TP53 | |
| Diethylamine SCHEMBL10371849 | 0.77 | TP53 (0.67) | TP53MEN1GLACYP2C19KMT2A | |
| SCHEMBL175585 | 0.77 | — | — | |
| SCHEMBL17435905 | 0.74 | — | — | |
| Tetrylammonium SCHEMBL17435843 | 0.74 | TSHR (0.44) | — | |
| Dimethylamine SCHEMBL17435848 | 0.74 | TSHR (0.31) | — | |
| Ammonia Solution, Strong SCHEMBL1115680 | 0.73 | TSHR (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2977349-B1 | METHOD FOR PRODUCING DISULFONYLAMINE ALKALI METAL SALT | NIPPON SODA CO (JP) | 2018-08-08 | — | — | EP | disclosed |
| US-9950929-B2 | Method for producing disulfonylamine alkali metal salt | NIPPON SODA CO., LTD. (JP) | 2018-04-24 | — | — | US | disclosed |
| EP-2977349-A1 | METHOD FOR PRODUCING DISULFONYLAMINE ALKALI METAL SALT | Nippon Soda Co., Ltd. (JP) | 2016-01-27 | — | — | EP | disclosed |
| US-20160016797-A1 | METHOD FOR PRODUCING DISULFONYLAMINE ALKALI METAL SALT | NIPPON SODA CO., LTD. (JP) | 2016-01-21 | — | — | US | disclosed |