Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 20/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1104994 | 0.82 | SCN9A (0.50) | SCN9ACYP2C9CYP3A4 | |
| SCHEMBL1104993 | 0.82 | SCN9A (0.66) | SCN9ACYP2C9CYP3A4 | |
| SCHEMBL9895917 | 0.81 | SCN9A (0.55) | SCN9ACYP2C9CYP3A4 | |
| SCHEMBL1094935 | 0.75 | SCN9A (0.53) | SCN9ACYP2C9CYP3A4 | |
| SCHEMBL16120766 | 0.75 | SCN9A (0.45) | SCN9ACYP2C9CYP3A4 | |
| SCHEMBL1095261 | 0.75 | SCN9A (0.69) | SCN9ACYP2C9CYP3A4 | |
| SCHEMBL9924965 | 0.74 | SCN9A (0.55) | SCN9ACYP2C9 | |
| SCHEMBL3475862 | 0.74 | SCN9A (0.45) | SCN9ACYP2C9CYP3A4 | |
| SCHEMBL319776 | 0.74 | SCN9A (0.56) | SCN9A | |
| SCHEMBL18013128 | 0.73 | SCN9A (0.64) | SCN9ACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2385938-A1 | SULFONAMIDE DERIVATIVES | Pfizer Limited (GB) | 2011-11-16 | — | — | EP | disclosed |
| US-8040476-B2 | Display device and method of producing the same | MITSUBISHI ELECTRIC CORPORATION (JP) | 2011-10-18 | — | — | US | disclosed |
| WO-2010079443-A1 | SULFONAMIDE DERIVATIVES | PFIZER LIMITED (GB) | 2010-07-15 | — | — | WO | disclosed |