Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 19/20 | 0.45 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1094461 | 0.87 | SCN9A (0.50) | SCN9ASCN8ACYP3A4CYP2C9SCN5A | |
| SCHEMBL28074465 | 0.77 | SCN9A (0.41) | SCN9ASCN8ACYP3A4CYP2C9SCN5A | |
| SCHEMBL28519988 | 0.77 | SCN8A (0.41) | SCN8A | |
| SCHEMBL16094574 | 0.74 | SCN9A (0.41) | SCN9ASCN8ACYP3A4CYP2C9SCN5A | |
| SCHEMBL3477862 | 0.74 | SCN9A (0.43) | SCN9A | |
| SCHEMBL1743618 | 0.74 | SCN9A (0.49) | SCN9ACYP3A4CYP2C9 | |
| SCHEMBL17509683 | 0.74 | SCN9A (0.40) | SCN9ASCN8ACYP3A4CYP2C9SCN5A | |
| SCHEMBL17523542 | 0.74 | SCN9A (0.39) | SCN9ASCN8ACYP3A4CYP2C9SCN5A | |
| SCHEMBL17961886 | 0.73 | SCN9A (0.40) | SCN9ASCN8ACYP3A4CYP2C9SCN5A | |
| SCHEMBL18013128 | 0.73 | SCN9A (0.64) | SCN9ASCN8ACYP2C9SCN5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100197655-A1 | SULFONAMIDE DERIVATIVES | Pfizer Limited Icagen, Inc. | 2010-08-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100197655-A1 | SULFONAMIDE DERIVATIVES | SULT2A1, SULT1A1, TPST2 | SCN9A 73/4885SCN8A 32/4885CYP3A4 133/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.