Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KA5 | O75582 | 5/20 | 0.55 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.39 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | AKT1 | P31749 | 1/20 | 0.30 |
| ▸ | AKT2 | P31751 | 1/20 | 0.30 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.30 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.30 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14050028 | 0.74 | RPS6KA5 (0.77) | RPS6KA5AKT1AKT2ROCK1AKT3 | |
| SCHEMBL16053930 | 0.72 | RPS6KA5 (0.48) | RPS6KA5ADORA2AADORA2BADORA1ADORA3 | |
| SCHEMBL4720745 | 0.72 | RPS6KA5 (1.00) | RPS6KA5AKT1AKT2ROCK1AKT3 | |
| SCHEMBL8276514 | 0.70 | AGTR1 (0.38) | RPS6KA5ADORA2AADORA2BADORA1ADORA3 | |
| SCHEMBL4064280 | 0.70 | RPS6KA5 (0.46) | RPS6KA5AKT1AKT2ROCK1AKT3 | |
| SCHEMBL16054218 | 0.70 | RPS6KA5 (0.41) | RPS6KA5 | |
| SCHEMBL17279264 | 0.67 | ADORA2A (0.38) | RPS6KA5ADORA2AADORA2BADORA1ADORA3 | |
| SCHEMBL31580070 | 0.66 | SMN1; SMN2 (0.40) | RPS6KA5 | |
| SCHEMBL15057859 | 0.64 | RPS6KA5 (0.42) | RPS6KA5 | |
| SCHEMBL17279272 | 0.61 | ADORA2A (0.40) | ADORA2AADORA2BADORA1ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170050963-A1 | MICROBICIDALLY ACTIVE IMIDAZOPYRIDINE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2017-02-23 | — | — | US | disclosed |
| US-9512120-B2 | Microbicidally active imidazopyridine derivatives | SYNGENTA PARTICIPATIONS AG (CH) | 2016-12-06 | — | — | US | disclosed |
| US-20160016949-A1 | MICROBICIDALLY ACTIVE IMIDAZOPYRIDINE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2016-01-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170050963-A1 | MICROBICIDALLY ACTIVE IMIDAZOPYRIDINE DERIVATIVES | IDO1, IDO2, FOXM1 | RPS6KA5 2731/4885ADORA2A 2060/4885ADORA2B 1612/4885 |
| US-20160016949-A1 | MICROBICIDALLY ACTIVE IMIDAZOPYRIDINE DERIVATIVES | IDO1, IDO2, FOXM1 | RPS6KA5 2731/4885ADORA2A 2060/4885ADORA2B 1612/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.