⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12018908 | 0.85 | — | — | |
| SCHEMBL13784687 | 0.83 | — | — | |
| SCHEMBL17244797 | 0.83 | — | — | |
| SCHEMBL20231017 | 0.81 | — | — | |
| SCHEMBL17244798 | 0.79 | EGLN1 (0.42) | — | |
| SCHEMBL10224697 | 0.79 | KDM4E (0.48) | — | |
| SCHEMBL27832109 | 0.77 | ALDH1A1 (0.44) | — | |
| SCHEMBL15426856 | 0.77 | ALDH1A1 (0.39) | — | |
| SCHEMBL15100636 | 0.76 | CACNA1C (0.38) | — | |
| SCHEMBL21705192 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023107696-A2 | INHIBITORS OF MENIN-MLL INTERACTION | BALA THERAPEUTICS, INC. (US) | 2023-06-15 | — | — | WO | disclosed |
| WO-2017182108-A1 | HYDROPHILICALLY MODIFIED POLYISOCYANURATE PLASTIC AND PROCESS FOR PRODUCTION THEREOF | COVESTRO DEUTSCHLAND AG (DE) | 2017-10-26 | — | — | WO | disclosed |
| EP-2344478-B1 | CC-1065 ANALOGS AND THEIR CONJUGATES | SYNTARGA BV (NL) | 2017-09-27 | — | — | EP | disclosed |
| US-20150322001-A1 | OMEGA-3 ANALOGUES | THE UNIVERSITY OF SYDNEY (AU) | 2015-11-12 | — | — | US | disclosed |
| EP-2387386-A2 | BETA-AMINO ESTER COMPOUNDS AND USES THEREOF | Living Proof, Inc. (US) | 2011-11-23 | — | — | EP | disclosed |
| US-8040383-B2 | Communication system, communication method, computer-readable medium and image shooting device | FUJIFILM CORPORATION (JP) | 2011-10-18 | — | — | US | disclosed |
| US-20110171291-A1 | PATHOLOGICALLY-ACTIVATED THERAPEUTICS | SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE | 2011-07-14 | — | — | US | disclosed |
| EP-2244697-A1 | THERAPEUTIC COMPOSITIONS | Shire Human Genetic Therapies, Inc. (US) | 2010-11-03 | — | — | EP | disclosed |
| WO-2010083379-A2 | BETA-AMINO ESTER COMPOUNDS AND USES THEREOF | LIVING PROOF, INC. (US) | 2010-07-22 | — | — | WO | disclosed |
| WO-2009097349-A1 | THERAPEUTIC COMPOSITIONS | SHIRE HUMAN GENETIC THERAPIES, INC. (US) | 2009-08-06 | — | — | WO | disclosed |