Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCI | P41743 | 4/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL175189 | 0.85 | NTRK1 (0.32) | — | |
| SCHEMBL166022 | 0.85 | NTRK1 (0.43) | — | |
| SCHEMBL175046 | 0.81 | PAK4 (0.33) | PRKCI | |
| SCHEMBL174490 | 0.79 | AURKB (0.41) | — | |
| SCHEMBL174933 | 0.79 | AURKA (0.40) | PRKCI | |
| SCHEMBL173922 | 0.79 | JAK2 (0.47) | PRKCI | |
| SCHEMBL174171 | 0.78 | NTRK1 (0.41) | — | |
| SCHEMBL174445 | 0.77 | CCNE2 (0.44) | — | |
| SCHEMBL174795 | 0.77 | FLT3 (0.36) | — | |
| SCHEMBL173271 | 0.76 | AURKB (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2611812-A1 | THIENOPYRIDINE AND THIENOPYRIMIDINE COMPOUNDS AND METHODS OF USE THEREOF | Ambit Biosciences Corporation (US) | 2013-07-10 | — | — | EP | disclosed |
| WO-2012030894-A1 | THIENOPYRIDINE AND THIENOPYRIMIDINE COMPOUNDS AND METHODS OF USE THEREOF | AMBIT BIOSCIENCES CORPORATION (US) | 2012-03-08 | — | — | WO | disclosed |
| WO-2012030894-A1 | THIENOPYRIDINE AND THIENOPYRIMIDINE COMPOUNDS AND METHODS OF USE THEREOF | AMBIT BIOSCIENCES CORPORATION (US) | 2012-03-08 | — | — | WO | disclosed |