SCHEMBL17439429

SCHEMBL17439429

COc1ccc(Oc2ccc3c4c(cccc24)C(=O)N(c2c(C(C)C)cccc2C(C)C)C3=O)c(N)c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ANPEP P15144 3/20 0.48
▸ SCN2A Q99250 1/20 0.44
▸ DPP4 P27487 3/20 0.43
▸ PRMT1 Q99873 1/20 0.43
▸ KMT2A Q03164 8/20 0.42
▸ MAPT P10636 4/20 0.42
▸ LMNA P02545 3/20 0.42
▸ HTT P42858 3/20 0.42
▸ ALDH1A1 P00352 3/20 0.42
▸ KDM4E B2RXH2 2/20 0.42
▸ POLB P06746 1/20 0.42
▸ PABPC1 P11940 1/20 0.42
▸ XBP1 P17861 1/20 0.42
▸ NFKB1 P19838 1/20 0.42
▸ SMARCA2 P51531 1/20 0.42
▸ NFKB2 Q00653 1/20 0.42
▸ RELA Q04206 1/20 0.42
▸ NR1H2 P55055 1/20 0.40
▸ NR1H3 Q13133 1/20 0.40
▸ USP2 O75604 5/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15995450 0.86 ANPEP (0.50) ANPEPDPP4PRMT1KMT2AMAPT
SCHEMBL17439423 0.85 LMNA (0.52) ANPEPDPP4PRMT1KMT2AMAPT
SCHEMBL14003757 0.84 ANPEP (0.56) ANPEPDPP4PRMT1KMT2AMAPT
SCHEMBL14003739 0.81 ANPEP (0.45) ANPEPDPP4PRMT1KMT2AMAPT
SCHEMBL3284746 0.81 MCL1 (0.52) ANPEPDPP4PRMT1KMT2AMAPT
SCHEMBL14003729 0.81 ANPEP (0.46) ANPEPDPP4PRMT1KMT2AMAPT
SCHEMBL14003719 0.80 ANPEP (0.56) ANPEPDPP4PRMT1KMT2AMAPT
SCHEMBL14003717 0.79 ANPEP (0.44) ANPEPDPP4PRMT1KMT2AMAPT
SCHEMBL14303997 0.78 KMT2A (0.49) SCN2APRMT1KMT2AMAPTLMNA
SCHEMBL14003713 0.78 ANPEP (0.43) ANPEPDPP4PRMT1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2961813-B1 NEW CLASS OF GREEN/YELLOW EMITTING PHOSPHORS BASED ON BENZOXANTHENE DERIVATIVES FOR LED LIGHTING PHILIPS LIGHTING HOLDING BV (NL) 2018-07-18 — — EP disclosed
US-9969932-B2 Class of green/yellow emitting phosphors based on benzoxanthene derivatives for LED lighting PHILIPS LIGHTING HOLDING B.V. (NL) 2018-05-15 — — US disclosed
US-9969932-B2 Class of green/yellow emitting phosphors based on benzoxanthene derivatives for LED lighting PHILIPS LIGHTING HOLDING B.V. (NL) 2018-05-15 — — US disclosed
US-20160017219-A1 NEW CLASS OF GREEN/YELLOW EMITTING PHOSPHORS BASED ON BENZOXANTHENE DERIVATIVES FOR LED LIGHTING SIGNIFY HOLDING B.V. (NL) 2016-01-21 — — US disclosed
US-20160017219-A1 NEW CLASS OF GREEN/YELLOW EMITTING PHOSPHORS BASED ON BENZOXANTHENE DERIVATIVES FOR LED LIGHTING SIGNIFY HOLDING B.V. (NL) 2016-01-21 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160017219-A1 NEW CLASS OF GREEN/YELLOW EMITTING PHOSPHORS BASED ON BENZOXANTHENE DERIVATIVES FOR LED LIGHTING CYBA, IK, P2RX4 ANPEP 3296/4885SCN2A 3024/4885DPP4 1404/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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