Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 15/20 | 0.47 |
| ▸ | MAP4K1 | Q92918 | 15/20 | 0.47 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KDM6B | O15054 | 1/20 | 0.42 |
| ▸ | KDM5C | P41229 | 1/20 | 0.42 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.42 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.42 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.42 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16881369 | 0.80 | KLKB1 (0.43) | KLKB1MAP4K1KDM4EALOX15L3MBTL1 | |
| SCHEMBL18370920 | 0.80 | KLKB1 (0.51) | KLKB1MAP4K1 | |
| SCHEMBL17447281 | 0.79 | KLKB1 (0.57) | KLKB1MAP4K1 | |
| SCHEMBL16891523 | 0.78 | KDM4E (0.49) | KLKB1MAP4K1KDM4EALOX15L3MBTL1 | |
| SCHEMBL18370186 | 0.78 | KLKB1 (0.52) | KLKB1MAP4K1 | |
| SCHEMBL582010 | 0.78 | KDM5B (0.56) | KLKB1MAP4K1KDM4EALOX15L3MBTL1 | |
| SCHEMBL16880817 | 0.77 | KDM4E (0.48) | KLKB1MAP4K1KDM4EALOX15L3MBTL1 | |
| SCHEMBL581173 | 0.77 | KDM5B (0.56) | KDM4EALOX15L3MBTL1KDM6BKDM5C | |
| SCHEMBL18371217 | 0.77 | KLKB1 (0.60) | KLKB1MAP4K1 | |
| SCHEMBL17920376 | 0.77 | KLKB1 (0.50) | KLKB1MAP4K1KDM4EALOX15KDM6B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3169325-A1 | THERAPEUTIC INHIBITORY COMPOUNDS | Lifesci Pharmaceuticals, Inc. (BB) | 2017-05-24 | — | — | EP | disclosed |
| WO-2016011209-A1 | THERAPEUTIC INHIBITORY COMPOUNDS | LIFESCI PHARMACEUTICALS, INC. (BB) | 2016-01-21 | — | — | WO | disclosed |