Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.49 |
| ▸ | KDM6B | O15054 | 1/20 | 0.49 |
| ▸ | KDM5C | P41229 | 1/20 | 0.49 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.49 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.44 |
| ▸ | KDM5B | Q9UGL1 | 6/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KDM5A | P29375 | 5/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.43 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.42 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.42 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.41 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16880817 | 0.87 | KDM4E (0.48) | KDM4EKDM4CKDM6BKDM5CKDM2A | |
| SCHEMBL581173 | 0.87 | KDM5B (0.56) | KDM4EKDM4CKDM6BKDM5CKDM2A | |
| SCHEMBL580585 | 0.87 | KDM5B (0.56) | KDM4EKDM4CKDM6BKDM5CKDM2A | |
| SCHEMBL30740808 | 0.85 | KDM4C (0.57) | KDM4EKDM4CKDM6BKDM5CKDM2A | |
| SCHEMBL348975 | 0.85 | KDM4C (0.57) | KDM4EKDM4CKDM6BKDM5CKDM2A | |
| SCHEMBL18371217 | 0.84 | KLKB1 (0.60) | KLKB1MAP4K1 | |
| SCHEMBL581463 | 0.84 | PTGS2 (0.46) | KDM4EKDM4CKDM6BKDM5CKDM2A | |
| SCHEMBL581445 | 0.84 | MRGPRX4 (0.46) | KDM4EKDM4CKDM6BKDM5CKDM2A | |
| SCHEMBL16880902 | 0.84 | KLKB1 (0.47) | KDM4EKDM4CKDM6BKDM5CKDM2A | |
| SCHEMBL581778 | 0.83 | MRGPRX4 (0.56) | KDM4EKDM4CKDM6BKDM5CKDM2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015103317-A1 | THERAPEUTIC INHIBITORY COMPOUNDS | LIFESCI PHARMACEUTICALS, INC. (BB) | 2015-07-09 | — | — | WO | disclosed |