Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 18/20 | 0.45 |
| ▸ | MAP4K1 | Q92918 | 14/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17442811 | 0.77 | KLKB1 (0.74) | KLKB1MAP4K1 | |
| SCHEMBL21657112 | 0.74 | KLKB1 (0.46) | KLKB1MAP4K1 | |
| SCHEMBL17442807 | 0.68 | KLKB1 (0.42) | KLKB1MAP4K1 | |
| SCHEMBL17442808 | 0.65 | KLKB1 (0.45) | KLKB1MAP4K1 | |
| SCHEMBL21190210 | 0.65 | KLKB1 (0.81) | KLKB1MAP4K1 | |
| SCHEMBL17920374 | 0.65 | GPR84 (0.47) | KLKB1MAP4K1 | |
| SCHEMBL18371154 | 0.64 | KLKB1 (0.83) | KLKB1MAP4K1 | |
| SCHEMBL16880946 | 0.64 | KLKB1 (0.78) | KLKB1MAP4K1 | |
| SCHEMBL18360096 | 0.64 | KLKB1 (0.65) | KLKB1MAP4K1 | |
| SCHEMBL18360274 | 0.64 | KLKB1 (0.65) | KLKB1MAP4K1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3169325-A1 | THERAPEUTIC INHIBITORY COMPOUNDS | Lifesci Pharmaceuticals, Inc. (BB) | 2017-05-24 | — | — | EP | disclosed |
| WO-2016011209-A1 | THERAPEUTIC INHIBITORY COMPOUNDS | LIFESCI PHARMACEUTICALS, INC. (BB) | 2016-01-21 | — | — | WO | disclosed |