Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Cefdinir. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 8/20 | 0.97 |
| ▸ | MAPT | P10636 | 5/20 | 0.97 |
| ▸ | ABCC4 | O15439 | 2/20 | 0.97 |
| ▸ | CNR1 | P21554 | 1/20 | 0.97 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.97 |
| ▸ | APEX1 | P27695 | 3/20 | 0.77 |
| ▸ | APAF1 | O14727 | 2/20 | 0.77 |
| ▸ | LMNA | P02545 | 2/20 | 0.77 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.77 |
| ▸ | TSHR | P16473 | 1/20 | 0.77 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.77 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.77 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.77 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.76 |
| ▸ | MMP2 | P08253 | 1/20 | 0.76 |
| ▸ | HPGD | P15428 | 1/20 | 0.63 |
| ▸ | NR1I2 | O75469 | 5/20 | 0.58 |
| ▸ | HTR2C | P28335 | 1/20 | 0.58 |
| ▸ | PPARG | P37231 | 2/20 | 0.56 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cefdinir SCHEMBL2532847 | 1.00 | TDP1 (0.97) | TDP1MAPTABCC4CNR1CTDSP1 | |
| Cefdinir SCHEMBL1744795 | 0.98 | TDP1 (0.97) | TDP1MAPTABCC4CNR1CTDSP1 | |
| Cefdinir SCHEMBL2534740 | 0.98 | TDP1 (0.97) | TDP1MAPTABCC4CNR1CTDSP1 | |
| Cefdinir SCHEMBL1744286 | 0.98 | TDP1 (0.97) | TDP1MAPTABCC4CNR1CTDSP1 | |
| Cefdinir SCHEMBL3297328 | 0.98 | TDP1 (1.00) | TDP1MAPTABCC4CNR1CTDSP1 | |
| Cefdinir SCHEMBL4114437 | 0.98 | TDP1 (1.00) | TDP1MAPTABCC4CNR1CTDSP1 | |
| Cefdinir SCHEMBL36996 | 0.98 | TDP1 (1.00) | TDP1MAPTABCC4CNR1CTDSP1 | |
| Cefdinir SCHEMBL6820723 | 0.98 | TDP1 (1.00) | TDP1MAPTABCC4CNR1CTDSP1 | |
| Cefdinir SCHEMBL5919457 | 0.98 | TDP1 (1.00) | TDP1MAPTABCC4CNR1CTDSP1 | |
| Cefdinir SCHEMBL16072816 | 0.98 | TDP1 (1.00) | TDP1MAPTABCC4CNR1CTDSP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2385054-B1 | CEFDINIR ACID DOUBLE SALT AND ITS PREPARATION | ZHEJIANG ADAMERCK BIOPHARMLABS INC (CN) | 2013-10-02 | — | — | EP | disclosed |
| EP-2385054-A1 | CEFDINIR ACID DOUBLE SALT AND ITS PREPARATION | Zhejiang Adamerck Biopharmlabs Inc. (CN) | 2011-11-09 | — | — | EP | disclosed |
| US-20110257388-A1 | CEFDINIR ACID DOUBLE SALT AND METHOD FOR PRODUCING THE SAME | ZHEJIANG ADAMERCK BIOPHARMLABS INC. (CN) | 2011-10-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110257388-A1 | CEFDINIR ACID DOUBLE SALT AND METHOD FOR PRODUCING THE SAME | SLC7A1, SLC10A1, SLC10A2 | TDP1 4442/4885MAPT 3969/4885ABCC4 3449/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.