SCHEMBL17442979

SCHEMBL17442979

Brc1cc(Br)cc(-c2c3nc(c(-c4cc(Br)cc(Br)c4)c4ccc([nH]4)c(-c4cc(Br)cc(Br)c4)c4nc(c(-c5cc(Br)cc(Br)c5)c5ccc2[nH]5)C=C4)C=C3)c1

nearest known ligand 0.53

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ TERT O14746 4/20 0.51
▸ TOP1 P11387 2/20 0.50
▸ CYCS P99999 3/20 0.49
▸ ENPP2 Q13822 1/20 0.47
▸ STAT3 P40763 1/20 0.43
▸ STAT1 P42224 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30382874 1.00 TERT (0.51) TERTTOP1CYCSENPP2STAT3
SCHEMBL3041824 0.83 TOP1 (0.60) TERTTOP1CYCSENPP2STAT3
SCHEMBL8182077 0.83 TOP1 (0.47) TERTTOP1CYCSENPP2STAT3
SCHEMBL29672144 0.81 TOP1 (0.58) TERTTOP1CYCSENPP2STAT3
SCHEMBL29737292 0.81 TOP1 (0.58) TERTTOP1CYCSENPP2STAT3
Zinc Ion SCHEMBL29875358 0.81 TOP1 (0.58) TERTTOP1CYCSENPP2STAT3
SCHEMBL30339537 0.81 TOP1 (0.58) TERTTOP1CYCSENPP2STAT3
SCHEMBL28672107 0.81 TOP1 (0.58) TERTTOP1CYCSENPP2STAT3
SCHEMBL29002878 0.81 TOP1 (0.58) TERTTOP1CYCSENPP2STAT3
Hydrochloric Acid SCHEMBL31547370 0.80 TOP1 (0.58) TERTTOP1CYCSENPP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3169722-B9 NANOPARTICLES CHROMITION LTD (GB) 2025-06-18 — — EP disclosed
EP-3169722-B1 NANOPARTICLES CHROMITION LTD (GB) 2025-02-12 — — EP disclosed
US-20210040260-A1 NANOPARTICLES CHROMITION LTD (GB) 2021-02-11 — — US disclosed
US-10703857-B2 Nanoparticles CHROMITION LIMITED (GB) 2020-07-07 — — US disclosed
US-20170198088-A1 NANOPARTICLES THE UNIVERSITY OF MANCHESTER (GB) 2017-07-13 — — US disclosed
EP-3169722-A1 NANOPARTICLES Chromition Limited (GB) 2017-05-24 — — EP disclosed
WO-2016009231-A1 NANOPARTICLES THE UNIVERSITY OF MANCHESTER (GB) 2016-01-21 — — WO disclosed
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