Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSTP1 | P09211 | 2/20 | 0.56 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.53 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.53 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.50 |
| ▸ | TOP1 | P11387 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 7/20 | 0.49 |
| ▸ | MAOA | P21397 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.47 |
| ▸ | GPR34 | Q9UPC5 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8616016 | 0.88 | GSTP1 (0.54) | GSTP1S1PR1S1PR3ALOX5TOP1 | |
| SCHEMBL16841041 | 0.88 | MAOB (0.51) | MAOBMAOAMEN1KMT2A | |
| SCHEMBL8612150 | 0.88 | GPR34 (0.53) | GSTP1S1PR1S1PR3MAOBMRGPRX4 | |
| SCHEMBL8613938 | 0.87 | GSTP1 (0.52) | GSTP1S1PR1S1PR3ALOX5TOP1 | |
| SCHEMBL8613447 | 0.87 | MAOB (0.55) | GSTP1S1PR1S1PR3ALOX5TOP1 | |
| SCHEMBL8616956 | 0.86 | FFAR1 (0.48) | GSTP1S1PR1S1PR3TOP1MAOB | |
| SCHEMBL8612975 | 0.86 | GSTP1 (0.51) | GSTP1S1PR1S1PR3ALOX5TOP1 | |
| SCHEMBL8612221 | 0.85 | MAOB (0.50) | ALOX5TOP1MAOBMAOANR4A2 | |
| SCHEMBL8614759 | 0.84 | GSTP1 (0.49) | GSTP1S1PR1S1PR3ALOX5TOP1 | |
| SCHEMBL8612156 | 0.84 | GSTP1 (0.49) | GSTP1S1PR1S1PR3ALOX5TOP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10450508-B2 | Bimesogenic compounds and mesogenic media | MERCK PATENT GMBH (DE) | 2019-10-22 | — | — | US | disclosed |
| US-10450508-B2 | Bimesogenic compounds and mesogenic media | MERCK PATENT GMBH (DE) | 2019-10-22 | — | — | US | disclosed |
| EP-3169749-B1 | BIMESOGENIC COMPOUNDS AND MESOGENIC MEDIA | MERCK PATENT GMBH (DE) | 2018-12-26 | — | — | EP | disclosed |
| US-20170210990-A1 | BIMESOGENIC COMPOUNDS AND MESOGENIC MEDIA | MERCK PATENT GMBH (DE) | 2017-07-27 | — | — | US | disclosed |
| US-20170210990-A1 | BIMESOGENIC COMPOUNDS AND MESOGENIC MEDIA | MERCK PATENT GMBH (DE) | 2017-07-27 | — | — | US | disclosed |
| US-20170210990-A1 | BIMESOGENIC COMPOUNDS AND MESOGENIC MEDIA | MERCK PATENT GMBH (DE) | 2017-07-27 | — | — | US | disclosed |
| EP-3169749-A1 | BIMESOGENIC COMPOUNDS AND MESOGENIC MEDIA | Merck Patent GmbH (DE) | 2017-05-24 | — | — | EP | disclosed |
| WO-2016008561-A1 | BIMESOGENIC COMPOUNDS AND MESOGENIC MEDIA | MERCK PATENT GMBH (DE) | 2016-01-21 | — | — | WO | disclosed |
| WO-2016008561-A1 | BIMESOGENIC COMPOUNDS AND MESOGENIC MEDIA | MERCK PATENT GMBH (DE) | 2016-01-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10450508-B2 | Bimesogenic compounds and mesogenic media | SP1, FOXM1, S100A11 | GSTP1 4122/4885S1PR1 1195/4885S1PR3 1861/4885 |
| US-20170210990-A1 | BIMESOGENIC COMPOUNDS AND MESOGENIC MEDIA | SP1, FOXM1, S100A11 | GSTP1 4167/4885S1PR1 1136/4885S1PR3 1795/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.