Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Nitric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | FDPS | P14324 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formaldehyde SCHEMBL28228888 | 0.85 | GABRA1 (0.44) | GABRA1GABRB2HDAC3HDAC1ALDH1A1 | |
| SCHEMBL11052 | 0.85 | GABRA1 (0.47) | GABRA1GABRB2HDAC3HDAC1ALDH1A1 | |
| Methane SCHEMBL27285897 | 0.83 | GABRA1 (0.45) | GABRA1GABRB2HDAC3HDAC1ALDH1A1 | |
| Iodide SCHEMBL11631414 | 0.83 | GABRA1 (0.45) | GABRA1GABRB2HDAC3HDAC1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL27937327 | 0.83 | GABRA1 (0.45) | GABRA1GABRB2HDAC3HDAC1ALDH1A1 | |
| Water SCHEMBL10657212 | 0.83 | GABRA1 (0.45) | GABRA1GABRB2HDAC3HDAC1ALDH1A1 | |
| SCHEMBL27670618 | 0.83 | GABRA1 (0.45) | GABRA1GABRB2HDAC3HDAC1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL5940132 | 0.83 | GABRA1 (0.45) | GABRA1GABRB2HDAC3HDAC1ALDH1A1 | |
| SCHEMBL27400123 | 0.79 | GABRA1 (0.39) | GABRA1GABRB2HDAC3HDAC1ALDH1A1 | |
| Anthraquinone SCHEMBL28264639 | 0.77 | ADORA2A (0.47) | GABRA1GABRB2HDAC3HDAC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3169818-B1 | PROCESS FOR SEPARATING PALLADIUM FROM THE OTHER METAL ELEMENTS PRESENT IN A NITRIC AQUEOUS PHASE AND USES THEREOF | COMMISSARIAT ENERGIE ATOMIQUE (FR) | 2018-10-17 | — | — | EP | disclosed |
| EP-3169818-A1 | PROCESS FOR SEPARATING PALLADIUM FROM THE OTHER METAL ELEMENTS PRESENT IN A NITRIC AQUEOUS PHASE AND USES THEREOF | Commissariat à l'Énergie Atomique et aux Énergies Alternatives (FR) | 2017-05-24 | — | — | EP | disclosed |
| WO-2016008932-A1 | PROCESS FOR SEPARATING PALLADIUM FROM THE OTHER METAL ELEMENTS PRESENT IN A NITRIC AQUEOUS PHASE AND USES THEREOF | Commissariat à l'énergie atomique et aux énergies alternatives (FR) | 2016-01-21 | — | — | WO | disclosed |