Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 2/20 | 0.36 |
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
| ▸ | ACACA | Q13085 | 1/20 | 0.36 |
| ▸ | PTGIR | P43119 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 5/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 5/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 5/20 | 0.35 |
| ▸ | GBA1 | P04062 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17444434 | 1.00 | CNR2 (0.36) | CNR2ACACBACACAPTGIRCHRM2 | |
| SCHEMBL25518973 | 0.93 | CNR2 (0.40) | CNR2ACACBACACAPTGIRCHRM2 | |
| SCHEMBL28097053 | 0.86 | CNR2 (0.36) | CNR2ACACBACACAPTGIRGBA1 | |
| SCHEMBL19267841 | 0.86 | MEN1 (0.46) | CNR2ACACBACACAMEN1MAPT | |
| SCHEMBL25284961 | 0.86 | MEN1 (0.42) | CNR2ACACBACACAPTGIRGBA1 | |
| SCHEMBL1428636 | 0.85 | CHRM3 (0.46) | CHRM2CHRM1CHRM3HDAC3HDAC1 | |
| SCHEMBL27593051 | 0.85 | PLG (0.39) | CNR2ACACBACACAPTGIRGBA1 | |
| SCHEMBL27593235 | 0.85 | CNR2 (0.36) | CNR2ACACBACACAPTGIRMEN1 | |
| SCHEMBL27557065 | 0.85 | MEN1 (0.37) | CNR2GBA1MEN1MAPTKMT2A | |
| SCHEMBL28255026 | 0.84 | MEN1 (0.48) | MEN1MAPTKMT2AATMHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3169368-A1 | LINKERS AND THEIR APPLICATION TOWARDS ADC | Medshine Discovery Inc. (CN) | 2017-05-24 | — | — | EP | disclosed |
| WO-2016008392-A1 | LINKERS AND THEIR APPLICATION TOWARDS ADC | MEDSHINE DISCOVERY INC. (CN) | 2016-01-21 | — | — | WO | disclosed |