Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 3/20 | 0.39 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.37 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.36 |
| ▸ | PDE2A | O00408 | 1/20 | 0.36 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.35 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.35 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15077207 | 0.93 | HCRTR1 (0.37) | HCRTR1HCRTR2 | |
| SCHEMBL2737589 | 0.93 | HSP90AA1 (0.39) | HSP90AA1HSP90AB1 | |
| SCHEMBL17445032 | 0.92 | HCRTR1 (0.41) | HCRTR1HCRTR2HSP90AA1HSP90AB1HSD11B1 | |
| SCHEMBL15077266 | 0.92 | HCRTR1 (0.38) | HCRTR1HCRTR2HSP90AA1HSP90AB1 | |
| SCHEMBL17445068 | 0.92 | MGLL (0.41) | HCRTR1HCRTR2GPBAR1 | |
| SCHEMBL2737735 | 0.91 | HCRTR1 (0.38) | HCRTR1HCRTR2HSP90AA1HSP90AB1HSD11B1 | |
| SCHEMBL15316912 | 0.91 | HSP90AA1 (0.37) | HSP90AA1HSP90AB1 | |
| SCHEMBL15077246 | 0.91 | HSP90AA1 (0.40) | HCRTR1HCRTR2HSP90AA1HSP90AB1GPBAR1 | |
| SCHEMBL17445023 | 0.90 | HCRTR1 (0.38) | HCRTR1HCRTR2 | |
| SCHEMBL15077270 | 0.89 | GPBAR1 (0.36) | HCRTR1HCRTR2HSP90AA1HSP90AB1GPBAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9238039-B2 | Pyrazolo[1,5-A]pyrimidines for antiviral treatment | GILEAD SCIENCES, INC. (US) | 2016-01-19 | — | — | US | disclosed |