Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.33 |
| ▸ | DAO | P14920 | 1/20 | 0.32 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL880047 | 0.63 | PTH1R (0.39) | EPHX2CRBN | |
| SCHEMBL879742 | 0.63 | PTH1R (0.39) | EPHX2CRBN | |
| Hydrochloric Acid SCHEMBL850588 | 0.62 | PTH1R (0.39) | EPHX2CRBN | |
| SCHEMBL879709 | 0.61 | PTH1R (0.38) | CRBN | |
| SCHEMBL13551818 | 0.60 | PTH1R (0.37) | CRBN | |
| SCHEMBL25876902 | 0.59 | SLC22A1 (0.35) | CRBN | |
| Hydrochloric Acid SCHEMBL5013959 | 0.58 | NEK2 (0.31) | — | |
| SCHEMBL2604297 | 0.57 | NEK2 (0.32) | CRBN | |
| SCHEMBL17113583 | 0.56 | HSD17B10 (0.34) | — | |
| SCHEMBL10461059 | 0.56 | SLC18A3 (0.64) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160016956-A1 | SPIROIMIDAZOLONE DERIVATIVE | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2016-01-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160016956-A1 | SPIROIMIDAZOLONE DERIVATIVE | WNK3, REN, SGK3 | EPHX2 4667/4885DAO 3212/4885CRBN 1932/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.