Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 9/20 | 0.52 |
| ▸ | RXRA | P19793 | 2/20 | 0.44 |
| ▸ | RXRB | P28702 | 2/20 | 0.44 |
| ▸ | RXRG | P48443 | 2/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.44 |
| ▸ | GFRA2 | O00451 | 1/20 | 0.42 |
| ▸ | GFRA3 | O60609 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 2/20 | 0.40 |
| ▸ | PPARD | Q03181 | 2/20 | 0.40 |
| ▸ | PPARA | Q07869 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.39 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.39 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1744684 | 1.00 | FFAR1 (0.52) | FFAR1RXRARXRBRXRGFFAR4 | |
| SCHEMBL1744696 | 1.00 | FFAR1 (0.52) | FFAR1RXRARXRBRXRGFFAR4 | |
| SCHEMBL1746731 | 0.89 | FFAR1 (0.45) | FFAR1GFRA2GFRA3MEN1KMT2A | |
| SCHEMBL1633344 | 0.81 | FFAR1 (0.57) | FFAR1FFAR4 | |
| SCHEMBL1633343 | 0.81 | FFAR1 (0.57) | FFAR1FFAR4 | |
| SCHEMBL1745432 | 0.81 | FFAR1 (0.57) | FFAR1FFAR4 | |
| SCHEMBL1745124 | 0.79 | GFRA3 (0.52) | FFAR1FFAR4GFRA2GFRA3 | |
| SCHEMBL1632826 | 0.76 | FFAR1 (0.64) | FFAR1FFAR4 | |
| SCHEMBL1744543 | 0.74 | FFAR1 (0.59) | FFAR1RXRARXRBRXRGFFAR4 | |
| SCHEMBL1745508 | 0.74 | FFAR1 (0.56) | FFAR1RXRARXRBRXRGFFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2385032-A1 | GPR40 Receptor function regulator | Takeda Pharmaceutical Company Limited (JP) | 2011-11-09 | — | — | EP | disclosed |
| US-7960369-B2 | Receptor function regulator | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2011-06-14 | — | — | US | disclosed |