SCHEMBL1746731

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1744685	0.89	FFAR1 (0.52)	FFAR1GFRA3GFRA2ALDH1A1HPGD
	SCHEMBL1744696	0.89	FFAR1 (0.52)	FFAR1GFRA3GFRA2ALDH1A1HPGD
	SCHEMBL1744684	0.89	FFAR1 (0.52)	FFAR1GFRA3GFRA2ALDH1A1HPGD
	SCHEMBL1744692	0.83	FFAR1 (0.52)	FFAR1GFRA3GFRA2ALDH1A1KMT2A
	SCHEMBL1744681	0.83	FFAR1 (0.52)	FFAR1GFRA3GFRA2ALDH1A1KMT2A
	SCHEMBL1745225	0.83	FFAR1 (0.52)	FFAR1GFRA3GFRA2ALDH1A1KMT2A
	SCHEMBL1744583	0.78	GFRA3 (0.49)	FFAR1GFRA3GFRA2RET
	SCHEMBL1746463	0.77	FFAR1 (0.53)	FFAR1ALDH1A1KMT2AMEN1IDO1
	SCHEMBL1747359	0.77	FFAR1 (0.51)	FFAR1GFRA3GFRA2ALDH1A1KMT2A
	SCHEMBL1745194	0.76	FFAR1 (0.54)	FFAR1GFRA3GFRA2ALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.