Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 18/20 | 0.44 |
| ▸ | MAP4K1 | Q92918 | 18/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | KDM5A | P29375 | 1/20 | 0.34 |
| ▸ | KDM5C | P41229 | 1/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.34 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17447279 | 0.93 | KLKB1 (0.44) | KLKB1MAP4K1PARP1KDM5AKDM5C | |
| SCHEMBL17442645 | 0.92 | KLKB1 (0.47) | KLKB1MAP4K1PARP1KDM5AKDM5C | |
| SCHEMBL18371162 | 0.81 | KLKB1 (0.44) | KLKB1MAP4K1KDM5CKDM4C | |
| SCHEMBL17442752 | 0.81 | KLKB1 (0.54) | KLKB1MAP4K1KDM5AKDM5CKDM4C | |
| SCHEMBL17442578 | 0.80 | KLKB1 (0.56) | KLKB1MAP4K1 | |
| SCHEMBL23279892 | 0.80 | PARP1 (0.50) | KLKB1MAP4K1PARP1KDM5AKDM5C | |
| SCHEMBL17442713 | 0.80 | KLKB1 (0.39) | KLKB1MAP4K1KDM5CKDM4CKDM5B | |
| SCHEMBL18371159 | 0.79 | MAPT (0.40) | KLKB1MAP4K1 | |
| SCHEMBL18370219 | 0.79 | KLKB1 (0.39) | KLKB1MAP4K1KDM5AKDM5CKDM4C | |
| SCHEMBL17442535 | 0.78 | KLKB1 (0.59) | KLKB1MAP4K1KDM5CKDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016011209-A1 | THERAPEUTIC INHIBITORY COMPOUNDS | LIFESCI PHARMACEUTICALS, INC. (BB) | 2016-01-21 | — | — | WO | disclosed |