Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 3/20 | 0.50 |
| ▸ | KLKB1 | P03952 | 15/20 | 0.47 |
| ▸ | MAP4K1 | Q92918 | 15/20 | 0.47 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.45 |
| ▸ | KDM5A | P29375 | 1/20 | 0.38 |
| ▸ | KDM5C | P41229 | 1/20 | 0.38 |
| ▸ | KDM5D | Q9BY66 | 1/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.38 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23279888 | 0.86 | PARP1 (0.47) | PARP1KLKB1MAP4K1MBOAT4 | |
| SCHEMBL17442684 | 0.86 | MBOAT4 (0.43) | PARP1KLKB1MAP4K1MBOAT4KDM5A | |
| SCHEMBL17909766 | 0.85 | KLKB1 (0.56) | PARP1KLKB1MAP4K1MBOAT4KDM5A | |
| SCHEMBL17442645 | 0.83 | KLKB1 (0.47) | PARP1KLKB1MAP4K1KDM5AKDM5C | |
| SCHEMBL17909754 | 0.81 | KLKB1 (0.59) | KLKB1MAP4K1 | |
| SCHEMBL17442524 | 0.81 | KLKB1 (0.62) | KLKB1MAP4K1 | |
| SCHEMBL17442526 | 0.81 | KLKB1 (0.67) | KLKB1MAP4K1 | |
| SCHEMBL18368869 | 0.80 | KLKB1 (0.56) | KLKB1MAP4K1 | |
| SCHEMBL17447315 | 0.80 | KLKB1 (0.53) | KLKB1MAP4K1 | |
| SCHEMBL17447319 | 0.80 | KLKB1 (0.44) | PARP1KLKB1MAP4K1KDM5AKDM5C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3169325-B1 | THERAPEUTIC INHIBITORY COMPOUNDS | ATTUNE PHARMACEUTICALS INC (US) | 2021-04-28 | — | — | EP | disclosed |